Department of Ophthalmology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Medicina (Kaunas). 2012;48(2):109-11. Epub 2012 Apr 5.
The aim of this study was to evaluate the quality of life in persons affected by age-related macular degeneration.
The study was performed in the Clinic of Ophthalmology, Hospital of Lithuanian University of Health Sciences. A total of 140 patients completed the Visual Functioning Questionnaire and the Hospital Anxiety and Depression Scale (HADS) during this prospective study. The patients were divided into two groups: patients with age-related macular degeneration (70 patients) and control patients (70 patients).
There was a significant difference in the quality of life between groups (P<0.0001). Analyzing patients with age-related macular degeneration within the group (patients with monocular or binocular disorders), significant differences in near vision (P=0.003), far vision (P=0.04), color vision (P=0.01), and social functioning (P=0.02) were observed. Mental health (r=0.326, P=0.02), dependency (r=0.340, P=0.02), and role difficulties (r=0.355, P=0.01) were found to be significantly associated with general vision in the age-related macular degeneration group.
Age-related macular degeneration appeared to have a great impact on the quality of life. General vision impairment caused by age-related macular degeneration affects patient's mental health, dependency, and role difficulties.
本研究旨在评估与年龄相关的黄斑变性患者的生活质量。
本研究在立陶宛健康科学大学医院眼科诊所进行。在这项前瞻性研究中，共有 140 名患者完成了视觉功能问卷和医院焦虑抑郁量表（HADS）。患者分为两组：年龄相关性黄斑变性患者（70 名）和对照组患者（70 名）。
两组间的生活质量存在显著差异（P<0.0001）。在年龄相关性黄斑变性组内（单眼或双眼障碍患者）分析，近视力（P=0.003）、远视力（P=0.04）、色觉（P=0.01）和社会功能（P=0.02）存在显著差异。年龄相关性黄斑变性组中，心理健康（r=0.326，P=0.02）、依赖性（r=0.340，P=0.02）和角色困难（r=0.355，P=0.01）与一般视力显著相关。
年龄相关性黄斑变性似乎对生活质量有很大影响。年龄相关性黄斑变性引起的一般视力损害会影响患者的心理健康、依赖性和角色困难。
