利用魁北克长白猪中连锁标记基因座（Phi、Po2、Pgd）预测氟烷（Hal）基因型。
Prediction of the halothane (Hal) genotypes by means of linked marker loci (Phi, Po2, Pgd) in Quebec Landrace pigs.
作者信息
Doizé F, Roux I, Martineau-Doizé B, DeRoth L
机构信息
Laboratoire de Biomédecine Comparée, Faculté de Médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec.
出版信息
Can J Vet Res. 1990 Oct;54(4):397-9.
Quebec Landrace pigs (n = 896) were halothane tested and blood samples were taken for the determination of Phi, Po2 and Pgd phenotypes. The incidence of the halothane positive pigs was 5.3%. The frequencies of the favorable alleles PhiA, Po2S and PdgA were respectively 29.2%, 39.6% and 64.4%. The highest linkage disequilibrium was found between Hal-Phi (0.0606) followed by Hal-Pgd (0.0428) and Hal-Po2 (-0.0308). Alleles PhiB, PgdB and Po2F were associated respectively with 97%, 81% and 74% of Haln haplotypes. It was concluded that a selection in order to increase the favorable marker loci PhiA and PgdA would reduce the Haln frequency in Quebec Landrace pigs.
对896头魁北克长白猪进行了氟烷检测，并采集血样以测定Phi、Po2和Pgd表型。氟烷阳性猪的发生率为5.3%。有利等位基因PhiA、Po2S和PdgA的频率分别为29.2%、39.6%和64.4%。发现Hal-Phi之间的连锁不平衡最高（0.0606），其次是Hal-Pgd（0.0428）和Hal-Po2（-0.0308）。等位基因PhiB、PgdB和Po2F分别与97%、81%和74%的Haln单倍型相关。得出的结论是，为增加有利标记位点PhiA和PgdA而进行的选择将降低魁北克长白猪中Haln的频率。
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