Epithelial-to-mesenchymal and endothelial-to-mesenchymal transition: from cardiovascular development to disease.
作者信息
Kovacic Jason C, Mercader Nadia, Torres Miguel, Boehm Manfred, Fuster Valentin
机构信息
Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1030, New York, NY 10029, USA.
出版信息
Circulation. 2012 Apr 10;125(14):1795-808. doi: 10.1161/CIRCULATIONAHA.111.040352.
Abstract
摘要
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本文引用的文献
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Thymosin beta 4 is dispensable for murine cardiac development and function.胸腺肽 β4 在小鼠心脏发育和功能中可有可无。
Circ Res. 2012 Feb 3;110(3):456-64. doi: 10.1161/CIRCRESAHA.111.258616. Epub 2011 Dec 8.
2
Adult cardiac-resident MSC-like stem cells with a proepicardial origin.成人心肌驻留 MSC 样干细胞，具有心外膜前体细胞起源。
Cell Stem Cell. 2011 Dec 2;9(6):527-40. doi: 10.1016/j.stem.2011.10.002.
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Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair.Wnt1/β-catenin 损伤反应激活心外膜和心肌成纤维细胞，促进心脏修复。
EMBO J. 2012 Jan 18;31(2):429-42. doi: 10.1038/emboj.2011.418. Epub 2011 Nov 15.
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Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes.心肌梗死后给予胸腺素β4 治疗不会将心外膜细胞重编程为心肌细胞。
J Mol Cell Cardiol. 2012 Jan;52(1):43-7. doi: 10.1016/j.yjmcc.2011.08.020. Epub 2011 Aug 26.
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A wt1-controlled chromatin switching mechanism underpins tissue-specific wnt4 activation and repression.WT1 控制的染色质转换机制为组织特异性 WNT4 的激活和抑制提供了基础。
Dev Cell. 2011 Sep 13;21(3):559-74. doi: 10.1016/j.devcel.2011.07.014. Epub 2011 Aug 25.
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FGF10/FGFR2b signaling is essential for cardiac fibroblast development and growth of the myocardium.FGF10/FGFR2b 信号对于心脏成纤维细胞的发育和心肌的生长是必不可少的。
Development. 2011 Aug;138(15):3331-40. doi: 10.1242/dev.064410.
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Protein kinase D2 controls cardiac valve formation in zebrafish by regulating histone deacetylase 5 activity.蛋白激酶 D2 通过调节组蛋白去乙酰化酶 5 的活性来控制斑马鱼心脏瓣膜的形成。
Circulation. 2011 Jul 19;124(3):324-34. doi: 10.1161/CIRCULATIONAHA.110.003301. Epub 2011 Jul 5.
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Effects of angiotensin II receptor blocker on myocardial endothelial-to-mesenchymal transition in diabetic rats.血管紧张素 II 受体阻滞剂对糖尿病大鼠心肌内皮-间质转化的影响。
Int J Cardiol. 2013 Jan 10;162(2):92-9. doi: 10.1016/j.ijcard.2011.06.052. Epub 2011 Jun 24.
9
WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways.WT1 通过 β-连环蛋白和视黄酸信号通路调节心外膜上皮向间充质转化。
Dev Biol. 2011 Aug 15;356(2):421-31. doi: 10.1016/j.ydbio.2011.05.668. Epub 2011 May 30.
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De novo cardiomyocytes from within the activated adult heart after injury.损伤后激活的成年心脏内的内源性心肌细胞。
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