Department of International Health, Johns Hopkins Bloomberg School of Public Health, Room E-8138, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
J Epidemiol Community Health. 2012 Aug;66(8):755-8. doi: 10.1136/jech-2011-200362. Epub 2012 Apr 6.
About a million newborns die each year in India, accounting for about a fourth of total global neonatal deaths. Infections are among the leading causes of neonatal mortality. Care practices immediately following delivery contribute to newborns' risk of infection and mortality.
This study examined the association between clean cord care practices and neonatal mortality in rural Uttar Pradesh, India.
The study used data from a household survey conducted to evaluate a community-based intervention program in two districts of Uttar Pradesh, India. Analysis included data from 5741 singleton live births delivered at home during 2005. The association between clean cord care (clean instrument used to cut cord, clean thread used to tie cord and antiseptics or nothing applied to the cord) and neonatal mortality was estimated using multivariate logistic regression models.
Thirty per cent of the study mothers practiced clean cord care. Neonatal mortality rate was significantly lower among newborns exposed to clean cord care (36.5/1000 live births, 95% CI 28.0 to 46.8) than those who did not practice (53.0/1000 live births, 95% CI 46.1 to 60.6). Clean cord care was associated with 37% lower neonatal mortality (OR=0.63; 95% CI 0.46 to 0.87) after adjusting for mother's age, education, caste/tribe, religion, household wealth, newborn thermal care practice and care-seeking during the first week after birth and study arms.
Promoting clean cord care practice among neonates in community-based maternal and newborn care programs has the potential to improve neonatal survival in rural India and similar other settings.
印度每年约有 100 万新生儿死亡,占全球新生儿死亡总数的约四分之一。感染是导致新生儿死亡的主要原因之一。分娩后立即采取的护理措施会增加新生儿感染和死亡的风险。
本研究旨在探讨印度北方邦农村地区清洁脐带护理与新生儿死亡之间的关联。
本研究使用了在印度北方邦两个地区进行的一项基于社区的干预项目的家庭调查数据。分析包括了 2005 年期间在家中分娩的 5741 例单胎活产的数据。使用多变量逻辑回归模型估计了清洁脐带护理(用于切断脐带的清洁器械、用于结扎脐带的清洁线以及应用于脐带的消毒剂或无任何处理)与新生儿死亡之间的关联。
研究中有 30%的母亲实施了清洁脐带护理。暴露于清洁脐带护理的新生儿死亡率明显低于未实施清洁脐带护理的新生儿(36.5/1000 活产,95%CI28.0 至 46.8)(53.0/1000 活产,95%CI46.1 至 60.6)。在调整了母亲的年龄、教育程度、种姓/部落、宗教、家庭财富、新生儿保暖护理实践以及出生后第一周的寻求医疗保健情况以及研究分组后,清洁脐带护理与新生儿死亡率降低 37%相关(OR=0.63;95%CI0.46 至 0.87)。
在基于社区的母婴保健项目中推广新生儿清洁脐带护理实践,有可能提高印度农村和类似其他环境中的新生儿存活率。