Pedamallu Srinivas B, Murphy Justin, Boyd Douglas, Martin-Hirsch Dominic, Al-Zwae Khaled
ENT, Calderdale Royal Hospital, Halifax, United Kingdom, HX3 0PW.
J Clin Med Res. 2009 Aug;1(3):181-3. doi: 10.4021/jocmr2009.07.1249. Epub 2009 Aug 20.
Malignant eccrine spiradenomas are exceedingly rare tumours. They are aggressive tumours normally arising in long-standing benign eccrine spiradenomas. We present a case of malignant eccrine spiradenoma of the right side of the face with direct intracranial extension without distant metastasis. A 48 years old woman presented with a large exophytic tumour on the right side of her face. Radiological imaging of the head and neck region revealed extensive invasion of the facial tissues around right orbit, maxilla and extension into the middle cranial fossa involving the right temporal lobe. She underwent craniotomy and debulking of the right temporal lobe and biopsy of the facial tumour. Histopathological findings were consistent with malignant eccrine spiradenoma. This is a rare case of facial malignant eccrine spiradenoma with direct intracranial extension with no distant metastasis. A literature search revealed that it is first case to be reported of this kind.
Eccrine carcinoma; Spiradenoma; Adnexal carcinoma; Malignant eccrine spiradenoma.
恶性小汗腺螺旋腺瘤是极其罕见的肿瘤。它们是侵袭性肿瘤，通常起源于长期存在的良性小汗腺螺旋腺瘤。我们报告一例右侧面部恶性小汗腺螺旋腺瘤伴直接颅内侵犯且无远处转移的病例。一名48岁女性，右侧面部出现一个巨大的外生性肿瘤。头颈部区域的影像学检查显示，右侧眼眶周围、上颌骨的面部组织广泛受侵，并延伸至中颅窝，累及右侧颞叶。她接受了开颅手术，对右侧颞叶进行了肿瘤大部切除，并对面部肿瘤进行了活检。组织病理学检查结果符合恶性小汗腺螺旋腺瘤。这是一例罕见的右侧面部恶性小汗腺螺旋腺瘤伴直接颅内侵犯且无远处转移的病例。文献检索显示，这是此类病例的首例报道。
小汗腺癌；螺旋腺瘤；附属器癌；恶性小汗腺螺旋腺瘤
