Department of Veterinary and Animal Science, University of Massachusetts, Amherst, MA 01003, USA.
J Med Entomol. 2012 Mar;49(2):336-42. doi: 10.1603/me11178.
Using the in vitro rearing system in conjunction with the hair tuft bioassay, NYDA and NYDA without fragrances formulations (92% wt:wt dimeticones) were 100% ovicidal (0% of treated eggs hatched) after an 8-h exposure of the eggs of the human head louse (Pediculus humanus capitis De Geer) following the manufacturer's instructions. Comparatively, 78 and 66% of eggs similarly exposed hatched after distilled deionized water or Nix (1% permethrin) treatments, respectively. NYDA and NYDA without fragrances formulations were also statistically and substantially more ovicidal than either distilled deionized water or Nix treatments after 10, 30 min, and 1 h exposures. Only the 10 min exposure of eggs to NYDA and NYDA without fragrances formulations resulted in hatched lice that survived to adulthood (5-8% survival). Of the lice that hatched from eggs exposed to NYDA formulations for 10 min, there were no significant differences in the time it took them to become adults, female fecundity or the viability of eggs laid by surviving females. The longevity of adults, however, was reduced after the 10 min treatments of eggs with NYDA and NYDA without fragrances formulations compared with either the distilled deionized water or Nix treatments.
采用体外饲养系统结合毛发丛生物测定法，NYDA 和不含香料的 NYDA 配方（92%重量：重量比二甲硅油）在按照制造商说明对人体头虱（Pediculus humanus capitis De Geer）的卵进行 8 小时暴露后，达到 100%杀卵效果（无孵化的卵）。相比之下，经过蒸馏水去离子水或 Nix（1%氯菊酯）处理后，类似暴露的卵分别有 78%和 66%孵化。NYDA 和不含香料的 NYDA 配方在暴露 10、30 分钟和 1 小时后，在统计学上和实质上比蒸馏水去离子水或 Nix 处理更具杀卵效果。只有在 10 分钟的时间内，卵暴露于 NYDA 和不含香料的 NYDA 配方中，才会孵化出能够存活至成年的虱子（5-8%的存活率）。从暴露于 NYDA 配方 10 分钟的卵中孵化出的虱子中，没有明显差异在它们成为成虫所需的时间、雌性生殖力或幸存雌性所产卵的活力。然而，与蒸馏水去离子水或 Nix 处理相比，在对卵进行 10 分钟的 NYDA 和不含香料的 NYDA 处理后，成虫的寿命缩短。
