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墨西哥蒙特雷地区临床分离株近平滑念珠菌种复合体的分子特征和抗真菌药敏性。

Molecular characterization and antifungal susceptibility of the Candida parapsilosis species complex of clinical isolates from Monterrey, Mexico.

机构信息

Departamento de Microbiología, Facultad de Medicina, Universidad Autónoma de Nuevo León , Monterrey, Nuevo León, México.

出版信息

Med Mycol. 2012 Oct;50(7):781-4. doi: 10.3109/13693786.2012.675526. Epub 2012 Apr 12.

DOI:10.3109/13693786.2012.675526
PMID:22493945
Abstract

Recently, it was proposed that the opportunistic yeast pathogen Candida parapsilosis was a complex composed of the following three species: Candida parapsilosis sensu stricto, Candida orthopsilosis, and Candida metapsilosis. A set of 344 clinical isolates of Candida parapsilosis from Monterrey, Mexico was re-identified by RFLP. Their antifungal susceptibility to fluconazole, caspofungin, anidulafungin and micafungin was determined using the Clinical and Laboratory Standards Institute M27-A3 protocol. Candida parapsilosis sensu stricto was the most frequent species, and was the only one which showed resistance to antifungals.

摘要

最近，有人提出机会性酵母病原体近平滑假丝酵母是由以下三个种组成的复合体：近平滑假丝酵母、近平滑假丝酵母和中间假丝酵母。一组来自墨西哥蒙特雷的 344 株临床分离近平滑假丝酵母通过 RFLP 重新鉴定。根据临床和实验室标准协会 M27-A3 方案测定其对氟康唑、卡泊芬净、阿尼芬净和米卡芬净的抗真菌敏感性。近平滑假丝酵母是最常见的物种，也是唯一对抗真菌药物有耐药性的物种。

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