Service of Pathology, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria and IFIMAV, Santander, Spain.
Pathol Res Pract. 2012 May 15;208(5):315-7. doi: 10.1016/j.prp.2012.03.002. Epub 2012 Apr 9.
Cardiac papillary fibroelastomas (PFEs) are uncommon valve tumors. Multiple PFEs at the same or different locations in the heart account for less than 10% of patients with PFE. We herein describe a case of an asymptomatic PFE of both pulmonary and aortic valves which was incidentally diagnosed by echocardiography in a 60-year-old woman. Both PFEs were removed surgically without valve replacement. To our knowledge, this combination of lesions has not been previously reported. Even though PFEs are classified as benign cardiac tumors, they can present serious complications, such as embolic episodes, mechanical obstruction or valvular dysfunction. Valve-sparing shave excision of the lesions can be readily accomplished in most instances with good long-term results. All surgically removed valvular lesions should be histopathologically examined to confirm the echocardiographic diagnosis.
心脏乳头状纤维弹性瘤（PFEs）是罕见的瓣膜肿瘤。同一心脏或不同部位的多个 PFEs 占 PFE 患者的比例不到 10%。本文描述了一例 60 岁女性患者无症状的肺动脉瓣和主动脉瓣 PFE，经超声心动图偶然诊断。两个 PFEs 均通过手术切除，无需瓣膜置换。据我们所知，这种病变组合以前尚未报道过。尽管 PFEs 被归类为良性心脏肿瘤，但它们可能会出现严重并发症，如栓塞发作、机械阻塞或瓣膜功能障碍。在大多数情况下，可以通过瓣膜保留的刮除术轻松完成病变的切除，并且长期预后良好。所有通过手术切除的瓣膜病变都应进行组织病理学检查以确认超声心动图诊断。
