Centre for Pharmacy and Department of Chemistry, University of Bergen, Bergen, Norway.
Fitoterapia. 2012 Jul;83(5):901-6. doi: 10.1016/j.fitote.2012.03.023. Epub 2012 Apr 1.
From stem barks of Capuronianthus mahafalensis (Meliaceae) endemic to Madagascar, a new protolimonoid named capulin containing a four membered ring in its side chain was isolated by repeated silica gel column chromatography. Its structure was determined by 1D and 2D NMR spectroscopy and high-resolution MS. To the best of our knowledge, this is the first time that a four-membered ring occurs in the side chain of protolimonoids.
从马达加斯加特有树种 Capuronianthus mahafalensis（楝科）的茎皮中，通过反复硅胶柱层析分离得到一种新的原贝壳杉烷类化合物 capulin，其侧链含有一个四元环。通过 1D 和 2D NMR 光谱和高分辨率 MS 确定了其结构。据我们所知，这是首次在原贝壳杉烷类化合物的侧链中出现四元环。
