Dagne E, Yenesew A, Capasso F, Mascolo N, Pinto A
Department of Chemistry, Addis Ababa University, Ethiopia.
Ethiop Med J. 1990 Oct;28(4):155-61.
In an attempt to ascertain the pharmacological basis of the use of the marketed traditional drug Taverniera abyssinica A. Rich. (Amharic name Dingetegna), crude extracts as well as purified substances of this plant were tested for their antipyretic and analgesic properties. Antipyretic activity was determined on rats made hyperthermic by yeast injection and analgesic activity was determined by the hot plate, as well as the acetic acid induced writhing, methods. The study showed that the plant possesses significant antipyretic and analgesic activities.
为了确定市售传统药物阿比西尼亚塔韦尼亚草(A. Rich.)(阿姆哈拉语名称为丁格泰尼亚)使用的药理学基础,对该植物的粗提物和纯化物质进行了解热和镇痛特性测试。通过给注射酵母致热的大鼠测定解热活性,通过热板法以及乙酸诱导扭体法测定镇痛活性。研究表明该植物具有显著的解热和镇痛活性。