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2000年至2010年间法国儿童抗生素消费量下降。

Decreased paediatric antibiotic consumption in France between 2000 and 2010.

作者信息

Dommergues Marie-Aliette, Hentgen Véronique

机构信息

Service de Pédiatrie, Centre Hospitalier de Versailles, Le Chesnay, France.

出版信息

Scand J Infect Dis. 2012 Jul;44(7):495-501. doi: 10.3109/00365548.2012.669840. Epub 2012 Apr 12.

Abstract

BACKGROUND

Antibiotic consumption is one of the main causes of bacterial resistance to antibiotics and a major public health problem worldwide, especially in France. A national campaign was implemented in 2001 to reduce the inappropriate use of antibiotics in France, and guidelines for the management of respiratory tract infections were published in 2005.

METHODS

In this study, data on paediatric outpatient antibiotic use in France between 2000 and 2010 were derived from prescribing panels of the Permanent Survey of Medical Prescription, which analyzed prescriptions by 835 French general practitioners and specialists.

RESULTS

Overall, antibiotic prescriptions decreased by 57.2% between 2001 and 2010 in children aged 0-24 months, by 50.0% in children aged 25 months to 6 y, and by 45.8% in children older than 6 y of age. In the 3 age groups, the greatest reduction was for rhinopharyngitis (83.4%) and the lowest was for otitis (22.4%). Because otitis is one of the most common diseases in childhood, the proportion of antibiotic prescriptions due to otitis in children aged 0-24 months consequently increased from 22.5% in 2000 to 42.3% in 2010.

CONCLUSION

Additional measures may be necessary to decrease antibiotic consumption related to otitis in young children.

摘要

背景

抗生素的使用是细菌对抗生素产生耐药性的主要原因之一,也是全球范围内的一个重大公共卫生问题,在法国尤为突出。2001年在法国开展了一项全国性运动,以减少抗生素的不当使用,2005年发布了呼吸道感染管理指南。

方法

在本研究中,2000年至2010年法国儿科门诊抗生素使用数据来自医疗处方永久调查的处方小组,该小组分析了835名法国全科医生和专科医生的处方。

结果

总体而言,2001年至2010年期间,0至24个月大儿童的抗生素处方减少了57.2%,25个月至6岁儿童减少了50.0%,6岁以上儿童减少了45.8%。在这三个年龄组中,减少最多的是鼻咽炎(83.4%),减少最少的是中耳炎(22.4%)。由于中耳炎是儿童最常见的疾病之一,因此0至24个月大儿童因中耳炎开具的抗生素处方比例从2000年的22.5%增至2010年的42.3%。

结论

可能需要采取额外措施来减少幼儿中耳炎相关的抗生素使用。

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