Atilgan Remzi, Celik Aygen, Boztosun Abdullah, Ilter Erdin, Yalta Tulin, Ozercan Resat
Obstetrics and Gynecology Division, Maltepe University Medicine Faculty Hospital Atatürk Cad. Maltepe Istanbul, Turkey.
Indian J Pathol Microbiol. 2012 Jan-Mar;55(1):52-5. doi: 10.4103/0377-4929.94856.
Cervical cancer is one of the most common female malignancy with high mortality rates in developing countries. Our purpose was to determine the prevalence of cervical cytologic abnormalities in population (strict Islamic religious area) and the detection rate of epithelial abnormalities by cervical cytology (CC).
A total of 32,026 conventional pap smear tests collected between January 2006 and January 2010 from three hospitals are retrospectively analyzed.
Total of 900 (2.8%) cases had epithelial abnormalities. The numbers and rates of epithelial abnormalities were as the followings: Atypical squamous cell of undetermined significance (ASCUS; n=615 [1.9%]); atypical squamous cell suspicious for high-grade squamous intraepithelial lesion (ASC-H; n=27 [0.1%]); atypical glandular cell of undetermined significance (AGUS; n=73 [0.2%]); low- grade squamous intraepitelial lesion (LSIL; n=147 [0.5%]); high- grade squamous intraepithelial lesion (HSIL; n=35 [0.1%]); and squamous cell carinoma (SCC; n=3 [0.0%]).
The prevalence of cervical cytological abnormality in our study was 2.8%. Recently, some conflicting results from the same population were published. More prospective studies with larger numbers are needed.
宫颈癌是发展中国家最常见的女性恶性肿瘤之一，死亡率很高。我们的目的是确定某人群（严格的伊斯兰宗教地区）宫颈细胞学异常的患病率以及通过宫颈细胞学检查（CC）检测上皮异常的比率。
回顾性分析了2006年1月至2010年1月期间从三家医院收集的总共32,026份传统巴氏涂片检查。
共有900例（2.8%）出现上皮异常。上皮异常的数量和比率如下：意义不明确的非典型鳞状细胞（ASCUS；n = 615 [1.9%]）；怀疑为高级别鳞状上皮内病变的非典型鳞状细胞（ASC-H；n = 27 [0.1%]）；意义不明确的非典型腺细胞（AGUS；n = 73 [0.2%]）；低级别鳞状上皮内病变（LSIL；n = 147 [0.5%]）；高级别鳞状上皮内病变（HSIL；n = 35 [0.1%]）；以及鳞状细胞癌（SCC；n = 3 [0.0%]）。
我们研究中宫颈细胞学异常的患病率为2.8%。最近，同一人群发表了一些相互矛盾的结果。需要更多更大规模的前瞻性研究。
