Filipi Kozeta, Xhani Anila
Institute of Public Health, Department of Epidemiology and Health Systems, Tirana, Albania E-mail :
Asian Pac J Cancer Prev. 2014;15(5):2129-32. doi: 10.7314/apjcp.2014.15.5.2129.
Cervical cancer is one of the most common female malignancies with high mortality rates in developing countries. Our purpose was to determine the prevalence of cervical cytological abnormalities by cervical cytology (CC) and the analysis of risk factors in Albanian population.
A total of 5,416 conventional pap smear tests collected between January 2009 and January 2012 from Tirana University Hospital Obstetrics-Gynecology "Queen Geraldine" were retrospectively analyzed.
A total of 258 (4.8%) cases had epithelial abnormalities. The numbers and rates were as follows: atypical squamous cell of undetermined significance (ASCUS; n=150 [2.76%]); atypical glandular cells of undetermined significance (AGUS; n=8 [0.14%]); low-grade squamous intraepithelial lesion (LSIL; n=87 [1.6%]); high- grade squamous intraepithelial lesion (HSIL; n=10 [0.18%]); and squamous cell carcinoma (SCC; n=3 [0.05%]).
The prevalence of cervical cytological abnormality in our study was 4.8%. A larger community-based study may establish the exact prevalence of malignant and premalignant lesions, so as to plan for future screening.
宫颈癌是发展中国家最常见的女性恶性肿瘤之一，死亡率很高。我们的目的是通过宫颈细胞学检查（CC）确定阿尔巴尼亚人群中宫颈细胞学异常的患病率，并分析危险因素。
回顾性分析了2009年1月至2012年1月间从地拉那大学医院妇产科“杰拉尔丁女王”收集的5416份传统巴氏涂片检查。
共有258例（4.8%）出现上皮异常。数量和比例如下：意义不明确的非典型鳞状细胞（ASCUS；n = 150 [2.76%]）；意义不明确的非典型腺细胞（AGUS；n = 8 [0.14%]）；低级别鳞状上皮内病变（LSIL；n = 87 [1.6%]）；高级别鳞状上皮内病变（HSIL；n = 10 [0.18%]）；以及鳞状细胞癌（SCC；n = 3 [0.05%]）。
我们研究中宫颈细胞学异常的患病率为4.8%。一项更大规模的基于社区的研究可能会确定恶性和癌前病变的确切患病率，以便为未来的筛查制定计划。
