Kim Young Ha, Lee Beom Jun, Lee Kyung Jin, Cho Jin Hee
Department of Otolaryngology-HNS, College of Medicine, The Catholic University of Korea, Seoul, Korea.
J Korean Neurosurg Soc. 2012 Feb;51(2):94-7. doi: 10.3340/jkns.2012.51.2.94. Epub 2012 Feb 29.
Tumors that metastasize to the pituitary gland are unusual, and are typically seen in elderly patients with diffuse malignant disease. The most common metastases to the pituitary are from primary breast and lung cancers. We report a 65-year-old woman with pituitary metastasis from breast cancer who presented with recent-onset left progressive deterioration of visual acuity and visual field. The clinical diagnosis was made after brain and sellar magnetic resonance imaging showed a large sellar mass compressing the optic chiasm and invading the pituitary stalk. An otorhinolaryngology and neurosurgery team removed the tumor via a transsphenoidal approach, and this procedure obtained symptomatic relief. Postoperatively, metastasis from breast invasive ductal adenocarcinoma was confirmed histologically. We report this unusual case with a review of the relevant literature.
转移至垂体的肿瘤较为罕见，通常见于患有弥漫性恶性疾病的老年患者。垂体最常见的转移瘤来自原发性乳腺癌和肺癌。我们报告了一名65岁患有乳腺癌垂体转移的女性，她出现了近期新发的左眼视力和视野进行性恶化。脑部和蝶鞍磁共振成像显示有一个巨大的蝶鞍肿块压迫视交叉并侵犯垂体柄后，做出了临床诊断。一个耳鼻喉科和神经外科团队通过经蝶窦入路切除了肿瘤，该手术缓解了症状。术后，经组织学证实为乳腺浸润性导管腺癌转移。我们报告了这一罕见病例并对相关文献进行了综述。
