AP-HP, Service de Gynécologie-Obstétrique et Médecine de la Reproduction, Hôpital Antoine Béclère, Clamart F-92141, France.
Reprod Biomed Online. 2012 Jun;24(6):611-3. doi: 10.1016/j.rbmo.2012.02.019. Epub 2012 Mar 6.
The French law regulating assisted reproductive technologies forbids donor spermatozoa to be available in case of failed testicular sperm extraction (TESE) performed on the day of oocyte retrieval. This article reports the first French live birth after intracytoplasmic sperm injection of donated spermatozoa into frozen-thawed oocytes cryopreserved following failure of TESE. By reinforcing the relevance of TESE performed on the day of oocyte retrieval, oocyte cryopreservation in couples having beforehand consented to go to sperm donation will avoid cycle cancellation and potentially lead to successful live birth. Therefore, it could modify the French policy of management of patients suffering from non-obstructive azoospermia.
法国法律规定,在卵母细胞取出日进行睾丸精子抽吸术(TESE)失败的情况下,禁止使用供精的精子。本文报告了首例在 TESE 失败后冷冻和解冻卵母细胞行卵胞浆内单精子注射(ICSI)获得的法国活产儿。通过强化 TESE 在卵母细胞取出日进行的相关性,在事先同意进行精子捐赠的夫妇中进行卵母细胞冷冻保存,将避免周期取消,并有可能导致成功的活产。因此,它可能会改变法国对非梗阻性无精子症患者的管理政策。