Liu Bing, Liu Jian-Ying, Zhang Wen-Feng, Jia Jun
Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China.
Int J Pediatr Otorhinolaryngol. 2012 Jul;76(7):1007-11. doi: 10.1016/j.ijporl.2012.03.020. Epub 2012 Apr 13.
To evaluate the incidence, types, and treatment outcomes of pediatric parotid tumors in Chinese population.
Pediatric salivary gland tumors treated at Stomatolgy Hospital, of Wuhan University, from 1990 to 2010, were analyzed retrospectively.
One hundred and two patients 18 years old or younger were diagnosed as parotid mass, of which 24 (23.5%) were parotid tumors. Of these patients, 11 (45.8%) were benign and 13 (54.2%) malignant. Hemangioma was the most frequent no-epithelial tumor. The most common benign epithelial tumor was pleomorphic adenoma (63.6%), and the most common malignant epithelial tumor was mucoepidermoid carcinoma (38.5%), with both of them showing a female to male predominance. The most common treatment was parotidectomy (83.3%).
Although pediatric parotid masses are unusual, they can represent a variety of pathological diagnoses, including malignancy. The intralesional injection can treat parotid hemangiomas in pediatric population effectively. Parotidectomy remains the mainstay treatment for both pediatric parotid gland benign and malignancies of epithelial cell origin. Adjuvant radiotherapy should be used judiciously in pediatric patients due to the higher risk of post-irradiation complications.
评估中国人群中小儿腮腺肿瘤的发病率、类型及治疗效果。
回顾性分析1990年至2010年在武汉大学口腔医院接受治疗的小儿唾液腺肿瘤。
102例18岁及以下患者被诊断为腮腺肿物,其中24例(23.5%)为腮腺肿瘤。这些患者中,11例(45.8%)为良性,13例(54.2%)为恶性。血管瘤是最常见的非上皮性肿瘤。最常见的良性上皮性肿瘤是多形性腺瘤(63.6%),最常见的恶性上皮性肿瘤是黏液表皮样癌(38.5%),两者均以女性居多。最常见的治疗方法是腮腺切除术(83.3%)。
尽管小儿腮腺肿物并不常见,但可能代表多种病理诊断,包括恶性肿瘤。瘤内注射可有效治疗小儿腮腺血管瘤。腮腺切除术仍然是小儿腮腺良性肿瘤及上皮细胞源性恶性肿瘤的主要治疗方法。由于放疗后并发症风险较高,小儿患者应谨慎使用辅助放疗。