Drivas Emmanouil I, Skoulakis Charalambos E, Symvoulakis Emmanouil K, Bizaki Argyro G, Lachanas Vassilios A, Bizakis John G
Department of Otorhinolaryngology, University of Crete, School of Medicine, Heraklion, Crete, Greece.
Med Sci Monit. 2007 Mar;13(3):CR136-40.
Salivary gland tumors constitute a highly heterogeneous group. There are few large epidemiological studies of benign and malignant salivary gland tumors in Greece. The aim of the present study was to define the pattern of parotid gland neoplasms on the island of Crete.
MATERIAL/METHODS: The medical records of 131 patients who underwent parotidectomy in the Otorhinolaryngology department of the University hospital of Heraklion over the last ten years were retrospectively reviewed. Gender and age of the patients, size, location, and histology of the tumors, as well as postoperative complications were analyzed and tabulated.
There were 101 (77.1%) benign parotid gland tumors and 30 (22.9%) of malignant ones. The most common benign tumor was pleomorphic adenoma (44.2%), while the most common malignant tumor was mucoepidermoid carcinoma (5.3%). The female-to-male ratio was 1.18/1.00. Median age was 48.2 years (range: 16-75 years) in patients with benign tumors and 65.4 years (range: 27-90 years) in patients with malignancy. After superficial parotidectomy, the most common postoperative complication was Frey syndrome (8.1%), while after total parotidectomy the most frequent complication was transient facial nerve palsy (45.5%).
On Crete, parotid gland tumors show epidemiological characteristics similar to studies worldwide. Benign parotid tumors are largely more frequent than malignant tumors. The most common benign parotid gland tumor was pleomorphic adenoma, while the most frequent malignant tumor was mucoepidermoid carcinoma. Future research needs to be done to better define the epidemiology of these tumors among the Greek population.
涎腺肿瘤是一个高度异质性的群体。希腊针对良性和恶性涎腺肿瘤的大型流行病学研究较少。本研究的目的是确定克里特岛腮腺肿瘤的发病模式。
材料/方法：回顾性分析了过去十年在伊拉克利翁大学医院耳鼻喉科接受腮腺切除术的131例患者的病历。分析并列表记录了患者的性别、年龄、肿瘤大小、位置、组织学类型以及术后并发症。
良性腮腺肿瘤101例（77.1%），恶性腮腺肿瘤30例（22.9%）。最常见的良性肿瘤是多形性腺瘤（44.2%），最常见的恶性肿瘤是黏液表皮样癌（5.3%）。女性与男性的比例为1.18/1.00。良性肿瘤患者的中位年龄为48.2岁（范围：16 - 75岁），恶性肿瘤患者的中位年龄为65.4岁（范围：27 - 90岁）。浅叶腮腺切除术后，最常见的术后并发症是味觉出汗综合征（8.1%），而全腮腺切除术后最常见的并发症是暂时性面神经麻痹（45.5%）。
在克里特岛，腮腺肿瘤的流行病学特征与全球研究相似。良性腮腺肿瘤比恶性肿瘤更为常见。最常见的良性腮腺肿瘤是多形性腺瘤，最常见的恶性肿瘤是黏液表皮样癌。未来需要开展进一步研究，以更好地明确希腊人群中这些肿瘤的流行病学情况。
