Fang Qi-Gen, Shi Shuang, Li Zhen-Ning, Zhang Xu, Liu Fa-Yu, Sun Chang-Fu
Department of Oromaxillofacial-Head and Neck Surgery, School of Stomatology, China Medical University, No. 117, Nanjing North Street, Heping District, Shenyang 110002, Liaoning, PR China.
Int J Pediatr Otorhinolaryngol. 2013 Aug;77(8):1252-4. doi: 10.1016/j.ijporl.2013.04.034. Epub 2013 Jun 6.
The purpose of this study was to evaluate our 25-year experience of pediatric salivary tumors.
Patients less than 19 years old with a diagnosis of salivary tumor were identified at Oral-maxillofacial Head and Neck Tumor Center, China Medical University from 1987 to 2011.
122 patients were included in our study, 105 tumors were benign and 17 were malignant. The most common involved site was parotid gland, pleomorphic adenoma represented 91.4% in benign group, and mucoepidermoid carcinoma represented 47.1% in malignant group. All tumors in submandibular gland were benign. Warthin's tumor was diagnosed in one patient. In our follow-up, no regional recurrences occurred in patients without neck dissection. The 5- and 10-year overall survival rates of patients with malignant salivary tumors were 81.8% and 66.7% respectively.
Epithelial salivary tumor was rare, parotid gland was most common involved site, pleomorphic adenoma and mucoepidermoid carcinoma were the most common benign and malignant tumor respectively. The prognosis of patients with malignant salivary tumors was not very favorable.
本研究旨在评估我们在小儿唾液腺肿瘤方面25年的经验。
对1987年至2011年在中国医科大学口腔颌面头颈肿瘤中心确诊为唾液腺肿瘤的19岁以下患者进行了研究。
本研究纳入122例患者，其中105例肿瘤为良性，17例为恶性。最常累及的部位是腮腺，良性组中多形性腺瘤占91.4%，恶性组中黏液表皮样癌占47.1%。下颌下腺的所有肿瘤均为良性。1例患者被诊断为沃辛瘤。在我们的随访中,未行颈部清扫术的患者未出现区域复发。恶性唾液腺肿瘤患者的5年和10年总生存率分别为81.8%和66.7%。
上皮性唾液腺肿瘤罕见，腮腺是最常累及的部位，多形性腺瘤和黏液表皮样癌分别是最常见的良性和恶性肿瘤。恶性唾液腺肿瘤患者的预后不太乐观。
