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一例双原发性癌:甲状腺乳头状癌伴颈部转移淋巴结间变性转化及乳腺癌

[A case of two primary carcinomas: thyroid papillary carcinoma with anaplastic transformation of metastatic cervical lymph node and breast cancer].

作者信息

Ohsumi S, Urakami J, Matsumori H, Sasaki S, Murakami M, Nose S

机构信息

Dept. of Surgery, Okayama National Hospital.

出版信息

Gan No Rinsho. 1990 Nov;36(14):2439-44.

PMID:2250366
Abstract

Reported is the case of a 70-year-old woman who, on diagnosis, was found to have a papillary carcinoma of the thyroid gland that showed an anaplastic transformation of a metastatic lesion of the right cervical lymph node. The primary lesion, however, contained no anaplastic areas. Simultaneously, she also was found to have a primary carcinoma of the left breast, an invasive ductal carcinoma. She thus received a total thyroidectomy with a right cervical node dissection, a modified radical mastectomy, and irradiation of the right cervical area, but no intensive chemotherapy was performed. Six months after the thyroidectomy, the anaplastic carcinoma caused her death. On autopsy, it was found to have involved the right cervical area, the lungs, the mediastinum, the right axilla, and the right kidney.

摘要

报告了一例70岁女性病例,诊断时发现患有甲状腺乳头状癌,其右侧颈部淋巴结转移灶出现了间变性转化。然而,原发灶未包含间变区域。同时,她还被发现患有左乳原发性癌,即浸润性导管癌。因此,她接受了全甲状腺切除术及右侧颈部淋巴结清扫术、改良根治性乳房切除术,并对右侧颈部区域进行了放疗,但未进行强化化疗。甲状腺切除术后六个月,间变性癌导致她死亡。尸检发现,该癌症已累及右侧颈部区域、肺部、纵隔、右侧腋窝和右肾。

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