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城乡人群眼内压分布:韩国 Namil 研究。

The distribution of intraocular pressure in urban and in rural populations: the Namil study in South Korea.

机构信息

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Am J Ophthalmol. 2012 Jul;154(1):99-106. doi: 10.1016/j.ajo.2012.01.009. Epub 2012 Apr 13.

Abstract

PURPOSE

To evaluate the intraocular pressure (IOP) distribution and its regional association in the South Korean population.

DESIGN

Cross-sectional, epidemiologic study.

METHODS

All participants underwent interview and the following ocular examinations: visual acuity measurement, autorefraction, pachymetry, anterior segment evaluation, slit-lamp examination, Goldmann applanation tonometry, binocular optic disc evaluation, fundus photography, and visual field test. Patients with ocular diseases other than mild senile cataract or with history of ocular surgery were excluded.

RESULTS

A total of 3191 subjects residing in urban and rural areas were recruited. Mean IOP of patients from the urban area was significantly higher than that of those from the rural area (14.45 ± 2.67 mm Hg vs 13.53 ± 2.76 mm Hg, P < .05). There was regional difference of mean IOP, even after controlling for different demographic factors in the 2 areas (P < .05). Average IOP in the right eye of the investigated sample of South Korean population was 14.10 ± 2.74 mm Hg. Multiple regression analysis showed positive correlation between mean IOP and central corneal thickness, vertical cup-to-disc ratio, history of hypertension, smoking, and female sex, whereas IOP tended to decrease by approximately 0.2 mm Hg when age increased by 10 years.

CONCLUSIONS

This is the first population-based epidemiologic study measuring IOP in the South Korean population. Mean IOP of the urban area was found to be significantly higher than the corresponding value of the rural area. Therefore, the regional difference, as well as other various factors, has to be considered in epidemiologic study of the distribution of IOP.

摘要

目的

评估韩国人群的眼压(IOP)分布及其区域性关联。

设计

横断面、流行病学研究。

方法

所有参与者均接受访谈和以下眼部检查:视力测量、自动验光、角膜厚度测量、眼前节评估、裂隙灯检查、压平眼压计测量、双眼视盘评估、眼底照相和视野检查。排除患有除轻度老年性白内障以外的眼部疾病或有眼部手术史的患者。

结果

共招募了居住在城市和农村地区的 3191 名受试者。城市地区患者的平均眼压明显高于农村地区患者(14.45 ± 2.67mmHg 比 13.53 ± 2.76mmHg,P <.05)。即使在控制了 2 个地区不同的人口统计学因素后,平均眼压仍存在区域性差异(P <.05)。韩国人群研究样本右眼的平均眼压为 14.10 ± 2.74mmHg。多元回归分析显示,平均眼压与中央角膜厚度、垂直杯盘比、高血压史、吸烟和女性呈正相关,而眼压随年龄增加 10 岁时大约降低 0.2mmHg。

结论

这是首次在韩国人群中进行的基于人群的眼压流行病学研究。发现城市地区的平均眼压明显高于农村地区。因此,在眼压分布的流行病学研究中,必须考虑区域性差异以及其他各种因素。

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