Saito Jun, Kim Soo Ryang, Kudo Masatoshi, Imoto Susumu, Ando Kenji, Nakajima Taisuke, Fukuda Katsumi, Otono Yumi, Kim Soo Ki, Komaki Takamitsu, Yano Hirohisa, Nakashima Osamu, Sugimoto Kayo, Matsuoka Toshiyuki
Department of Gastroenterology, Kobe Asahi Hospital, Japan.
Intern Med. 2012;51(8):885-90. doi: 10.2169/internalmedicine.51.6904. Epub 2012 Apr 15.
We describe a well-differentiated hepatocellular carcinoma (HCC) with alcohol-related liver cirrhosis in a 69-year-old man. Ultrasonography (US) disclosed a 10 mm hypoechoic nodule in segment 4; Sonazoid contrast-enhanced US and gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) revealed no defect in either the Kupffer phase or the hepatobiliary phase. Computed tomography during hepatic arteriography (CTHA), however, revealed a hypovascular nodule, but CT during arterial portography showed no perfusion defect. Histological analysis indicated a well-differentiated HCC. Thus, our detection of well-differentiated HCC disclosed by only CTHA attested to the efficiency of this modality, suggesting that it is more sensitive than Gd-EOB-GTPA-enhanced MRI.
我们描述了一名69岁男性患有与酒精相关的肝硬化的高分化肝细胞癌（HCC）。超声检查（US）发现肝段4有一个10毫米的低回声结节；Sonazoid超声造影和钆乙氧基苄基二乙三胺五乙酸（Gd-EOB-DTPA）增强磁共振成像（MRI）在库普弗期或肝胆期均未发现缺损。然而，肝动脉造影计算机断层扫描（CTHA）显示一个低血运结节，但门静脉造影CT未显示灌注缺损。组织学分析表明为高分化HCC。因此，我们仅通过CTHA检测到高分化HCC证明了这种检查方式的有效性，表明它比Gd-EOB-GTPA增强MRI更敏感。
