Theodore D R, Meier-Ruge W, Abraham J
Department of Neurological Sciences, Cristian Medical College Hospital, Vellore, India.
Microvasc Res. 1990 Sep;40(2):199-205. doi: 10.1016/0026-2862(90)90019-n.
Microvasculature of the right caudate nucleus and insular cortex of monkeys with their right middle cerebral artery occluded was morphometrically measured with an image analysis system at 1/2, 4, 12, 24, and 48 hr and 2 weeks. A biphasic change in the microvasculature was observed. In the first phase up to 12 hr an increase in the number and length of the total microvasculature, visualized by alkaline phosphatase staining, along with a reduction in the number and length of the perfused part of the microvasculature, visualized by India ink perfusion, was observed. In the second phase after 48 hr, the number and length of the total microvascular bed as well as the perfused functional bed were significantly reduced.
用图像分析系统对右侧大脑中动脉闭塞的猴子的右侧尾状核和岛叶皮质的微血管系统在1/2小时、4小时、12小时、24小时、48小时和2周时进行形态测量。观察到微血管系统呈双相变化。在长达12小时的第一阶段，通过碱性磷酸酶染色可见的总微血管数量和长度增加，同时通过印度墨汁灌注可见的微血管灌注部分的数量和长度减少。在48小时后的第二阶段，总微血管床以及灌注的功能床的数量和长度均显著减少。
