Kim Chul, Kim Duk You, Moon Chang Jin
Department of Rehabilitation Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul 139-707, Korea.
Ann Rehabil Med. 2011 Jun;35(3):375-80. doi: 10.5535/arm.2011.35.3.375. Epub 2011 Jun 30.
To observe the prognostic influences of the cardiac rehabilitation (CR) program in Korean acute myocardial infarction (AMI) patients during the first year after an occurrence of the disease.
A total of 141 AMI patients who underwent percutaneous coronary intervention (PCI) were recruited consecutively for this study and divided into the CR group and the control group. The CR group completed the phase 2 CR program in the hospital for a period of 6-8 weeks and maintained self-exercise in their community by exercise prescription for a year after AMI. We performed a prospective comparison of the patients' demographic data, high sensitive C-reactive protein (hs-CRP) level after the 4-month CR program, and the rate of recurrence (AMI, re-hospitalization, positive coronary angiogram, needed revascularization procedure, or death) between the two groups.
Compared to the control group (0.33±0.48 mg/dl), the hs-CRP level was lower in the CR group (0.18±0.32 mg/dl) after 4 months of exercise. The recurrence rate was lower (10%, 7/69) in the CR group, compared to the control group (24%, 17/72, p<0.05). The number of disease-free days was larger in the CR group (354±38.34), compared to the control group (316±99.96, p<0.05). In a comparison of statistical methods used for testing the equality of two survivor distributions, the CR group showed a lower recurrence rate than the control group (p<0.05).
Participation in the CR program designed for AMI patients who underwent PCI-induced normalization of the serum hs-CRP level and lowering of the recurrence rate by 14% during the first year.
观察心脏康复(CR)计划对韩国急性心肌梗死(AMI)患者发病后第一年预后的影响。
本研究连续招募了141例行经皮冠状动脉介入治疗(PCI)的AMI患者,分为CR组和对照组。CR组在医院完成了为期6 - 8周的第二阶段CR计划,并在AMI后通过运动处方在社区进行了一年的自我锻炼。我们对两组患者的人口统计学数据、4个月CR计划后的高敏C反应蛋白(hs-CRP)水平以及复发率(AMI、再次住院、冠状动脉造影阳性、需要血管重建手术或死亡)进行了前瞻性比较。
运动4个月后,CR组的hs-CRP水平(0.18±0.32mg/dl)低于对照组(0.33±0.48mg/dl)。CR组的复发率(10%,7/69)低于对照组(24%,17/72,p<0.05)。CR组的无病天数(354±38.34)多于对照组(316±99.96,p<0.05)。在比较用于检验两个生存分布是否相等的统计方法时,CR组的复发率低于对照组(p<0.05)。
参与为行PCI的AMI患者设计的CR计划可使血清hs-CRP水平正常化,并在第一年将复发率降低14%。