Ahonen Jouni, Nuutila Mika
HUS, naistenklinikka.
Duodecim. 2012;128(6):569-77.
HELLP syndrome (hemolysis, elevated liver enzymes, low platelets) is a severe microcirculatory disturbance during pregnancy, associated with pre-eclampsia, but it may occur also without it. In HELLP maternal morbidity and mortality have increased. Typical complications include coagulation disorder, acute respiratory failure, acute renal failure, infections, central nervous system symptoms, hepatic failure and bleeding, and premature ablation of the placenta. The only effective means to treat the syndrome during pregnancy is termination of pregnancy.
HELLP综合征(溶血、肝酶升高、血小板减少)是妊娠期一种严重的微循环障碍,与子痫前期相关,但也可能在无子痫前期的情况下发生。HELLP综合征会增加孕产妇的发病率和死亡率。典型的并发症包括凝血障碍、急性呼吸衰竭、急性肾衰竭、感染、中枢神经系统症状、肝衰竭和出血,以及胎盘早剥。孕期治疗该综合征的唯一有效方法是终止妊娠。