Teo Jin Yao, Cheong Crystal Shuk-Jin, Wong Chow Yin
Department of General Surgery, Singapore General Hospital, Singapore.
ANZ J Surg. 2012 May;82(5):325-8. doi: 10.1111/j.1445-2197.2012.06045.x. Epub 2012 Mar 27.
Phyllodes tumours are increasingly being discovered incidentally in young patients after excision of a seemingly innocuous breast lump. The clinical course of this group of patients has not been well-described, especially in the Asian population.
A retrospective review of 44 consecutive patients below 25 years of age undergoing surgery for phyllodes tumours at our institution from 1992 to 2010 was conducted. Clinico-pathological data, local recurrence rates and margin involvement were recorded.
The majority of the patients had benign lesions treated with simple enucleation, and there were no local recurrences documented after a mean and median length of follow-up of 47.6 and 29.5 months, respectively.
We conclude that in young Asian patients who present with benign phyllodes tumours, simple excision, followed by close follow-up is sufficient, regardless of surgical margin status.
叶状肿瘤越来越多地在年轻患者切除看似无害的乳腺肿块后偶然被发现。这组患者的临床病程尚未得到充分描述,尤其是在亚洲人群中。
对1992年至2010年在我们机构接受叶状肿瘤手术的44例连续25岁以下患者进行回顾性研究。记录临床病理数据、局部复发率和切缘受累情况。
大多数患者的良性病变采用单纯摘除术治疗,平均随访47.6个月、中位随访29.5个月后,均未记录到局部复发。
我们得出结论,对于出现良性叶状肿瘤的年轻亚洲患者,无论手术切缘情况如何,单纯切除后密切随访就足够了。