Center for Neurorestoratology, Beijing Rehabilitation Center, Beijing, P.R. China.
Cell Transplant. 2012;21 Suppl 1:S3-11. doi: 10.3727/096368912X633725.
Neurorestoratology is a newborn and emerging distinct discipline in the neuroscience family. Its establishment will definitely speed up the advance of this promising frontier realm. A worldwide association for Neurorestoratology and several official journals covering this discipline have recently been set up. Clinical practice has demonstrated that the sequelae of damages and diseases of the CNS can be functionally restored to some degree. Obstacles that hinder the promising methods of Neurorestoratology to be translated from the bench to the bedside include political, governmental, religious, ethical, economic, and scientific factors or in most instances they work in combination. Falsehoods against the recognition of neurorestoratology include: 1) no therapeutic method is currently available that suggests that it is possible to repair, even partially, neurological functions; 2) according to the media, a cure will be very soon found for patients with severe spinal cord injury, brain trauma, and progressively deteriorated CNS degenerative diseases; 3) randomizing double blind control designed studies are the only gold standard for clinical study; self-comparison designed studies should be ignored and neglected. Future directions for neurorestoratology include the comparison and integration of current and upcoming available neurorestoration methods to look for the optimization regimes, and edit and publish clinical neurorestoratology treatment guidelines.
神经修复学是神经科学领域中一个新兴的独特学科。它的建立必将加速这一充满希望的前沿领域的发展。最近成立了一个全球性的神经修复学会和几个专门报道这一学科的官方期刊。临床实践已经证明，中枢神经系统损伤和疾病的后遗症可以在一定程度上得到功能恢复。阻碍神经修复学的有前途的方法从实验室转化到临床的障碍包括政治、政府、宗教、伦理、经济和科学因素，或者在大多数情况下，这些因素是联合作用的。反对神经修复学认可的错误观点包括：1）目前没有治疗方法表明有可能修复，甚至部分修复神经功能；2）根据媒体报道，严重脊髓损伤、脑外伤和逐渐恶化的中枢神经系统退行性疾病患者很快就会找到治愈方法；3）随机双盲对照设计研究是临床研究的唯一金标准；自身对照设计研究应该被忽视和忽略。神经修复学的未来方向包括比较和整合当前和即将出现的神经修复方法，以寻找最佳治疗方案，并编辑和发布临床神经修复治疗指南。
