Velasco-Montes Javier, Oriñuela-González Itziar, Sanjuán-López Ainhoa Z
Hospital Santiago Apóstol, Servicio de Medicina Interna, Vitoria-Gasteiz, España.
Actas Esp Psiquiatr. 2012 Mar-Apr;40(2):97-9. Epub 2012 Mar 1.
Quetiapine is one of the drugs used most in current Psychiatry due to its therapeutic efficiency and clinical safety. We report the case of a 26-year-old male patient with severe mental retardation due to Y-chromosome partial deletion who initiated treatment with quetiapine for the control of his aggressiveness, and who developed severe rhabdomyolysis two weeks later. In spite of the confirmed clinical safety of quetiapine, doctors must monitor the appearance of rare but serious adverse effects as that presented in this clinical case.
喹硫平因其治疗效果和临床安全性，是目前精神病学中使用最为广泛的药物之一。我们报告了一例26岁男性患者，因Y染色体部分缺失导致严重智力发育迟缓，开始使用喹硫平治疗以控制其攻击性，两周后出现严重横纹肌溶解。尽管喹硫平临床安全性已得到确认，但医生仍必须监测罕见但严重的不良反应，如本临床病例中出现的情况。
