Center for Management of Complex Chronic Care, Hines VA Hospital, Hines, IL 60141, USA.
Spinal Cord. 2012 Sep;50(9):682-5. doi: 10.1038/sc.2012.31. Epub 2012 Apr 17.
Cross-sectional survey of veterans with spinal cord injuries and disorders (SCI/D).
To describe sleep dysfunction (independent of sleep apnea) in persons with traumatic and non-traumatic SCI/D, and to examine characteristics and health outcomes independently associated with sleep dysfunction unrelated to sleep apnea.
Seven Veterans Affairs SCI care facilities in the United States.
Mailed cross-sectional survey with follow-up calls completed by end of 2008. Bivariate analyses to compare measures outcomes in persons with SCI/D who were dysfunctional sleepers vs those who were not. Multivariate logistic regression used to identify variables independently associated with dysfunctional sleep in veterans with SCI/D.
Overall, 49% of the sample had sleep dysfunction unrelated to sleep apnea. In this subgroup, bivariate analyses showed that a greater proportion of dysfunctional sleepers than non-dysfunctional sleepers were current smokers, had problems with drinking alcohol, hypertension, asthma, chronic obstructive pulmonary disease (COPD) and problematic weight gain. Variables independently associated with higher odds of dysfunctional sleep included white race, being a current smoker, problems with drinking alcohol, asthma, COPD and problematic weight gain.
Consistent with epidemiological evidence for the general population, we found significant associations of sleep dysfunction with weight gain, smoking, alcohol misuse and select chronic conditions (COPD, asthma). Sustained sleep dysfunction may contribute to health deterioration and mortality, highlighting the need to address the high prevalence of sleep dysfunction (independent of sleep apnea) in persons with SCI/D. In particular, efforts aimed at modifying problematic weight gain, alcohol misuse and smoking are warranted in this cohort to improve sleep.
对脊髓损伤和疾病（SCI/D）退伍军人进行的横断面调查。
描述创伤性和非创伤性 SCI/D 患者的睡眠功能障碍（与睡眠呼吸暂停无关），并研究与睡眠呼吸暂停无关的睡眠功能障碍相关的特征和健康结果。
美国 7 个退伍军人事务 SCI 护理机构。
邮寄横断面调查，并于 2008 年底完成随访电话。使用双变量分析比较有睡眠功能障碍和无睡眠功能障碍的 SCI/D 患者的测量结果。使用多元逻辑回归确定与 SCI/D 退伍军人睡眠功能障碍独立相关的变量。
总体而言，样本中有 49%的人存在与睡眠呼吸暂停无关的睡眠功能障碍。在这个亚组中，双变量分析显示，与非睡眠功能障碍者相比，更多的睡眠功能障碍者是当前吸烟者，存在饮酒问题，患有高血压、哮喘、慢性阻塞性肺疾病（COPD）和体重问题。与睡眠功能障碍几率较高独立相关的变量包括白人种族、当前吸烟、饮酒问题、哮喘、COPD 和体重问题。
与一般人群的流行病学证据一致，我们发现睡眠功能障碍与体重增加、吸烟、饮酒过量和某些慢性疾病（COPD、哮喘）存在显著关联。持续的睡眠功能障碍可能导致健康恶化和死亡，这凸显了需要解决 SCI/D 患者中普遍存在的睡眠功能障碍（与睡眠呼吸暂停无关）。特别是，需要努力改变体重问题、饮酒过量和吸烟，以改善这一人群的睡眠。
