Department of Gastroenterology and Hepatology, University Medical Center, University of Groningen, Groningen, The Netherlands.
World J Gastroenterol. 2012 Apr 7;18(13):1502-7. doi: 10.3748/wjg.v18.i13.1502.
To investigate whether the small bowel transit time (SBTT) influences the diagnostic yield of capsule endoscopy (CE).
Six hundred and ninety-one consecutive CE procedures collected in a database were analyzed. SBTT and CE findings were recorded. A running mean for the SBTT was calculated and correlated to the diagnostic yield with a Spearman's correlation test. Subgroup analyses were performed for the various indications for the procedure.
There was a positive correlation between the diagnostic yield and SBTT (Spearman's rho 0.58, P < 0.01). Positive correlations between diagnostic yield and SBTT were found for the indication obscure gastrointestinal bleeding (r = 0.54, P < 0.01), for polyposis and carcinoid combined (r = 0.56, P < 0.01) and for the other indications (r = 0.90, P <0.01), but not for suspected Crohn's disease (r = -0.40).
The diagnostic yield in small bowel capsule endoscopy is positively correlated with the small bowel transit time. This is true for all indications except for suspected Crohn's disease.
研究小肠通过时间（SBTT）是否会影响胶囊内镜（CE）的诊断效果。
分析数据库中收集的 691 例连续 CE 检查。记录 SBTT 和 CE 检查结果。计算 SBTT 的移动平均值，并与诊断效果进行 Spearman 相关分析。对不同适应证进行亚组分析。
诊断效果与 SBTT 呈正相关（Spearman 相关系数 0.58，P < 0.01）。在不明原因胃肠道出血（r = 0.54，P < 0.01）、息肉病和类癌合并症（r = 0.56，P < 0.01）和其他适应证（r = 0.90，P < 0.01）的情况下，诊断效果与 SBTT 之间存在正相关，但在疑似克罗恩病（r = -0.40）的情况下不存在相关性。
小肠胶囊内镜的诊断效果与小肠通过时间呈正相关。除疑似克罗恩病外，这对所有适应证均适用。
