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2400 例中国患者 OMOM 胶囊内镜的应用领域、诊断效果及发现。

Fields of applications, diagnostic yields and findings of OMOM capsule endoscopy in 2400 Chinese patients.

机构信息

Capsule Endoscopy Study Group, Department of Gastroenterology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China.

出版信息

World J Gastroenterol. 2010 Jun 7;16(21):2669-76. doi: 10.3748/wjg.v16.i21.2669.

Abstract

AIM

To retrospectively analyze the fields of application, diagnostic yields and findings of OMOM capsule endoscopy in Chinese patients.

METHODS

A database including 2400 Chinese patients who received OMOM capsule endoscopy in 27 endoscopy centers in China was retrieved from the Jianshan Science and Technology Ltd. OMOM capsule endoscopy database. The patient's age, gender, fields of application, the potentially relevant findings, pyloric transit time (PTT), small bowel transit time (SBTT), and complete small-bowel examination rate (CSER) were recorded and analyzed.

RESULTS

Two thousand four hundred patients aged 9-91 years (mean, 49 years), of whom 1510 were males (62.9%), underwent 2400 OMOM capsule endoscopy procedures. One thousand two hundred and thirty two (51.3%) were referred with obscure gastrointestinal bleeding (OGIB), 642 (26.8%) with abdominal pain, and 223 (9.3%) with chronic diarrhea. The overall diagnostic yield was 47.7% (1144/2400). The diagnostic yield of OMOM capsule endoscopy in OGIB subgroup was much higher than in the non-OGIB subgroup (62.4% vs 32.1%, P < 0.001). The most common findings of the small bowel in Chinese patients with OGIB were arteriovenous malformation (28.1%) and tumors (18.9%). There was no significant difference in the diagnostic yield between the male and female patients with OGIB. However, the diagnostic yield in patients aged more than 60 was higher than in patients aged less than 60 (69.8% vs 58.9%, P < 0.001). The median PTT was 41 min (range: 1-544 min) and the mean SBTT was 247.2 +/- 88.9 min. The overall CSER was 86.8%.

CONCLUSION

The OMOM capsule endoscopy is a valuable tool for small bowel evaluation with good overall diagnostic yield and CSER.

摘要

目的

回顾性分析 OMOM 胶囊内镜在我国患者中的应用领域、诊断率和检查结果。

方法

从江苏金山科技有限公司的 Jianshan 科技有限公司 OMOM 胶囊内镜数据库中检索了 27 家内镜中心的 2400 例中国患者的数据库,包括患者年龄、性别、应用领域、潜在相关发现、幽门口通过时间(PTT)、小肠通过时间(SBTT)和全小肠检查率(CSER)。

结果

2400 例年龄 9-91 岁(平均年龄 49 岁)的患者中,男性 1510 例(62.9%)接受了 2400 例 OMOM 胶囊内镜检查。1232 例(51.3%)因不明原因胃肠道出血(OGIB)就诊,642 例(26.8%)因腹痛就诊,223 例(9.3%)因慢性腹泻就诊。OMOM 胶囊内镜检查的总体诊断率为 47.7%(1144/2400)。OGIB 亚组的 OMOM 胶囊内镜诊断率明显高于非 OGIB 亚组(62.4%比 32.1%,P<0.001)。中国 OGIB 患者小肠最常见的发现是动静脉畸形(28.1%)和肿瘤(18.9%)。OGIB 男性和女性患者的诊断率无显著差异。然而,年龄大于 60 岁的患者的诊断率高于年龄小于 60 岁的患者(69.8%比 58.9%,P<0.001)。中位 PTT 为 41 分钟(范围:1-544 分钟),平均 SBTT 为 247.2+/-88.9 分钟。总体 CSER 为 86.8%。

结论

OMOM 胶囊内镜是一种评估小肠的有价值的工具,具有良好的总体诊断率和 CSER。

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