Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA.
J Periodontol. 2013 Feb;84(2):143-51. doi: 10.1902/jop.2012.120079. Epub 2012 Apr 17.
Maternal periodontal disease diagnosed by a detailed oral health examination is associated with preeclampsia. Our objective was to measure the association between maternal self-report of oral symptoms/problems, oral hygiene practices, and/or dental service use before or during pregnancy and severe preeclampsia.
A written questionnaire was administered to pregnant females at the time of prenatal ultrasound and outcomes were ascertained by chart abstraction. The χ(2) test compared maternal oral symptoms/problems, hygiene practices, and dental service use between females with severe preeclampsia versus normotensive females. Multivariable logistic regression was used to calculate adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for severe preeclampsia.
A total of 48 (10%) of 470 females reported ≥2 oral symptoms/problems in the 6 months before pregnancy and 77 (16%) since pregnancy. Fifty-one (11%) reported previous periodontal treatment. Twenty-eight (6%) of 470 developed severe preeclampsia. Females with a history of periodontal treatment were more likely to develop severe preeclampsia (aOR = 3.71; 95% CI = 1.40 to 9.83) than females without a history of periodontal treatment. Self-reported oral health symptoms/problems, oral hygiene practices, or dental service use before or during pregnancy were not associated with severe preeclampsia when considered in the context of other maternal risk factors.
Maternal self-report of previous periodontal treatment before pregnancy is associated with severe preeclampsia.
通过详细的口腔健康检查诊断出的母体牙周病与子痫前期有关。我们的目的是测量母体在怀孕前或怀孕期间自我报告的口腔症状/问题、口腔卫生习惯和/或牙科服务使用情况与重度子痫前期之间的关联。
在产前超声检查时向孕妇发放书面问卷，并通过病历摘录确定结果。使用 χ(2)检验比较有重度子痫前期的女性与血压正常的女性之间的口腔症状/问题、卫生习惯和牙科服务使用情况。使用多变量逻辑回归计算重度子痫前期的调整后优势比（aOR）和 95%置信区间（CI）。
共有 470 名女性中的 48 名（10%）在怀孕前 6 个月内报告了≥2 种口腔症状/问题，77 名（16%）自怀孕以来报告了这些问题。51 名（11%）报告了以前的牙周治疗。470 名女性中有 28 名（6%）发展为重度子痫前期。有牙周治疗史的女性发生重度子痫前期的可能性是没有牙周治疗史的女性的 3.71 倍（95%CI = 1.40 至 9.83）。在考虑其他母体危险因素的情况下，怀孕前或怀孕期间自我报告的口腔健康症状/问题、口腔卫生习惯或牙科服务使用与重度子痫前期无关。
怀孕前自我报告的既往牙周治疗与重度子痫前期有关。
