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青少年精神科住院患者中大麻使用的临床相关性。

Clinical correlates of cannabis use among adolescent psychiatric inpatients.

机构信息

Shalvata Mental Health Center, POB 94 Hod Hasharon, 45100, Israel.

出版信息

Eur Psychiatry. 2012 Aug;27(6):470-5. doi: 10.1016/j.eurpsy.2011.11.002. Epub 2012 Apr 17.

Abstract

OBJECTIVES

This study sought to determine the clinical correlates of adolescents with cannabis use and no additional drug use (CU) compared to adolescents with no drug use (NDU) among a group of adolescent psychiatric inpatients in Israel.

METHODS

Two hundred and thirty-six patients consecutively admitted to an adolescent inpatient unit at a university-affiliated mental health center in Israel during a 3-year period were screened. Individuals with polydrug use were excluded from the study.

RESULTS

Prevalence of cannabis use was 13%. In the CU group, 39% were diagnosed with attention deficit and disruptive behavior disorders compared with 16% in the NDU group. Antipsychotics were the most common medications prescribed in both groups. Mood stabilizers were more frequently prescribed to CU than to NDU patients (39% vs 16%, respectively). A higher prevalence of alcohol abuse and criminal behaviors was found among CU compared to NDU patients (61% and 39% vs 6% and 4%, respectively).

CONCLUSIONS

The high prevalence of disruptive behaviors and frequent treatment with antipsychotics and mood stabilizers in the CU group may be related to the strong association between externalizing behavior and cannabis use and the non-specific pharmacological treatment of disruptive behaviors. Formal screening for cannabis use should be considered in psychiatric facilities. Specifically, adolescents with disruptive behaviors could benefit from early interventions, before and after cannabis initiation.

摘要

目的

本研究旨在确定以色列一组青少年精神科住院患者中,与无其他药物使用(NDU)的青少年相比,有大麻使用但无其他药物使用(CU)的青少年的临床相关性。

方法

在以色列一所大学附属心理健康中心的青少年住院部,连续 3 年对 236 名患者进行了筛查。排除了多药使用的个体。

结果

大麻使用率为 13%。在 CU 组中,39%被诊断为注意缺陷和破坏性行为障碍,而 NDU 组为 16%。在两组中,抗精神病药物是最常用的药物。与 NDU 患者相比,CU 患者更常开心境稳定剂(39%比 16%)。与 NDU 患者相比,CU 患者中酒精滥用和犯罪行为的发生率更高(61%和 39%比 6%和 4%)。

结论

CU 组中破坏性行为的高发生率以及抗精神病药物和心境稳定剂的频繁使用可能与外在行为与大麻使用之间的强烈关联以及破坏性行为的非特异性药物治疗有关。在精神科机构应考虑进行大麻使用的正式筛查。特别是,有破坏性行为的青少年可能受益于在大麻使用之前和之后进行早期干预。

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