Hong Lei, Wang Zhe, Yuan Lin, Tan Jianhua, Wang Lixin, Qu Guangbo, Zhang Daoqiang, Lin Ronghai, Liu Sijin
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
J Nanosci Nanotechnol. 2012 Jan;12(1):365-7. doi: 10.1166/jnn.2012.5765.
In spite of great advances in conventional cancer diagnosis and treatment, the early recognition and characterization for various cancers remain a technological bottleneck. The combined characteristics of board absorption and narrow emission make quantum dots (QDs) desirable fluorescent labels for cancer imaging and other applications in the biomedical field. In the current study, to the best of our knowledge, we first evidenced the preferential accumulation of QDs in cytoplasm of breast cancer cells. QDs therefore reveal considerable potentials in both tumor imaging and therapeutic application.
尽管传统癌症诊断和治疗取得了巨大进展，但各种癌症的早期识别和特征描述仍然是一个技术瓶颈。量子点（QDs）具有宽吸收和窄发射的综合特性，使其成为生物医学领域癌症成像和其他应用中理想的荧光标记物。在本研究中，据我们所知，我们首次证明了量子点在乳腺癌细胞质中的优先积累。因此，量子点在肿瘤成像和治疗应用中都显示出相当大的潜力。
