在无血清培养基中生长的哺乳动物细胞产生干扰素。
Interferon production by mammalian cells grown in a serum-free medium.
作者信息
Pumper R W, Molander L
出版信息
In Vitro. 1979 May;15(5):388-92. doi: 10.1007/BF02616147.
PMID:225261
Abstract
Interferon, produced by rabbit heart cells grown in a serum-free medium, failed to protect rabbit heart serum-free cells, but protected rabbit heart serum-containing-medium cells against vaccinia and vesicular stomatitis virus. Interferon produced in serum-free cells had a greater species specificity than that produced in serum-containing media. The difference in activity was shown to be due to lack of adsorption by serum-free-medium cells.
摘要
在无血清培养基中培养的兔心脏细胞产生的干扰素，不能保护兔心脏无血清细胞，但能保护含兔心脏血清培养基的细胞免受牛痘病毒和水疱性口炎病毒的侵害。在无血清细胞中产生的干扰素比在含血清培养基中产生的干扰素具有更高的种属特异性。活性差异表明是由于无血清培养基细胞缺乏吸附作用所致。
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