Clinic of Anesthesiology and Intensive Care, Vilnius University, Siltnamių 29, LT-04130, Vilnius, Lithuania.
Knee Surg Sports Traumatol Arthrosc. 2013 Mar;21(3):641-5. doi: 10.1007/s00167-012-1971-0. Epub 2012 Apr 13.
Optimal postoperative analgesia after anterior cruciate ligament repair remains challenging. The objective of this prospective experimental clinical study was to compare the postoperative analgesic efficacy of two infusion regimens of 0.1 % bupivacaine administered via perineural femoral catheter.
Forty adult ASA I and II patients undergoing anterior cruciate ligament reconstruction were enrolled. Surgery was performed under spinal anesthesia combined with femoral nerve block. A perineural femoral catheter was connected to the patient controlled analgesia infusion pump filled with 0.1 % bupivacaine for postoperative pain control. Subjects were assigned to one of two groups according to the bupivacaine infusion regimen: (1) 5 mL/h basal infusion with on-demand 5 mL boluses and 30-min refractive periods, and (2) only on-demand 5 mL boluses and 15-min refractive periods. Quality of postoperative analgesia, adjunctive analgesic consumption, and overall patient satisfaction were recorded for 48 h.
Pain control was better in Group I on the day of surgery (P = 0.001) and on the first postoperative day at rest and during mobilization (P = 0.02 and P = 0.009). On the second postoperative day, only pain control during mobilization was better in Group I (P = 0.047). Adjunctive analgesic consumption and patient satisfaction were similar.
Perineural femoral infusion of on-demand 5 mL boluses of 0.1 % bupivacaine combined with 5 mL/h basal infusion was more efficient than on-demand regimen alone for postoperative pain management after reconstruction of anterior cruciate ligament of the knee.
II.
前交叉韧带修复术后的最佳镇痛仍然具有挑战性。本前瞻性实验临床研究的目的是比较两种 0.1%布比卡因经股神经旁输注方案用于术后镇痛的效果。
纳入 40 例 ASA I 和 II 级接受前交叉韧带重建的成年患者。手术在脊髓麻醉联合股神经阻滞下进行。股神经旁留置导管与患者自控镇痛泵相连,泵内输注 0.1%布比卡因用于术后疼痛控制。根据布比卡因输注方案将患者分为两组:(1)5ml/h 基础输注+按需 5ml 推注+30min 反射期,(2)仅按需 5ml 推注+15min 反射期。记录 48 小时内术后镇痛质量、辅助镇痛药物消耗和总体患者满意度。
手术当天(P=0.001)和术后第 1 天静息时(P=0.02)和活动时(P=0.009),组 I 的疼痛控制更好。术后第 2 天,组 I 仅在活动时的疼痛控制更好(P=0.047)。辅助镇痛药物消耗和患者满意度相似。
与仅按需方案相比,股神经旁输注 0.1%布比卡因+5ml/h 基础输注的按需 5ml 推注方案更有效地管理膝关节前交叉韧带重建术后的疼痛。
II 级。