Lewitzka U, Bauer M, Felber W, Müller-Oerlinghausen B
Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden, Deutschland.
Nervenarzt. 2013 Mar;84(3):294-306. doi: 10.1007/s00115-012-3542-5.
Treatment of patients with suicidal behaviour is one of the most challenging tasks for health care professionals. Due to the high mortality, morbidity and costs related to suicide, the development of treatment and preventive strategies for suicidal behaviour have been a focus of psychiatric research. For lithium, one of the oldest pharmacological agents used in psychiatry, anti-suicidal effects have been found since the early 90s in many international studies. Despite this unambiguous evidence and corresponding recommendations in national and international guidelines for the acute and maintenance therapy of affective disorders, the use of lithium is still underrepresented. The following article provides a review of studies investigating the anti-suicidal effects of lithium in affective disorders. Clinical implications for the treatment of affective disorders are discussed.
对有自杀行为的患者进行治疗，是医疗保健专业人员面临的最具挑战性的任务之一。由于与自杀相关的高死亡率、发病率和成本，自杀行为治疗与预防策略的开发一直是精神病学研究的重点。锂盐作为精神病学中使用最久的药物之一，自90年代初以来在许多国际研究中都发现了其抗自杀作用。尽管有明确的证据以及国家和国际指南中针对情感障碍急性和维持治疗的相应建议，但锂盐的使用仍然不足。以下文章综述了有关锂盐对情感障碍抗自杀作用的研究，并讨论了其对情感障碍治疗的临床意义。
