Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Hacettepe University, 06100 Ankara, Turkey.
Biol Trace Elem Res. 2012 Oct;149(1):117-22. doi: 10.1007/s12011-012-9400-2. Epub 2012 Apr 18.
Toxic metals are one of the significant groups of chemical contaminants that humans are exposed to by oral, inhalation, and dermal routes. Exposure to these chemicals begins with intrauterine life and continues during lactation period at the first years of life. Breastfeeding has a much more special place than other nutrition options for infants. However, when possibility of contaminant transfer by breast milk is considered, its safety and quality is essential. Regarding infant and mother health and limited number of information on this field in Turkey, measuring contamination levels in breast milk is important. Therefore, in the present study, lead (Pb), cadmium (Cd), nickel (Ni), and arsenic (As) levels were measured by atomic absorption spectrometry in 64 breast milk samples obtained from mothers from Ankara, Turkey. Pb and Ni levels in breast milk samples were found to be 391.45±269.01 μg/l and 43.94±33.82 μg/l (mean ± SD), respectively. Cd was found only in one of 64 samples, and the level was 4.62 μg/l. As level was below the limit of quantification (LOQ, 7.6 μg/l) in all samples. These findings will accurately direct strategies and solutions of protection against contaminants in order to reduce their levels in biological fluids.
有毒金属是人类通过口服、吸入和皮肤途径接触的重要化学污染物群体之一。这些化学物质的暴露始于宫内生命，并在生命的头几年的哺乳期继续。母乳喂养对于婴儿来说比其他营养选择更具特殊意义。然而，当考虑到母乳中污染物转移的可能性时，其安全性和质量至关重要。鉴于婴儿和母亲的健康以及土耳其在这一领域的信息有限，测量母乳中的污染水平很重要。因此，在本研究中，通过原子吸收光谱法测量了来自土耳其安卡拉的 64 份母乳样本中的铅（Pb）、镉（Cd）、镍（Ni）和砷（As）水平。母乳样本中的 Pb 和 Ni 水平分别为 391.45±269.01μg/l 和 43.94±33.82μg/l（平均值±标准差）。在 64 个样本中仅发现 Cd 存在于其中一个样本中，其水平为 4.62μg/l。在所有样本中，As 水平均低于定量限（LOQ，7.6μg/l）。这些发现将准确指导针对污染物的保护策略和解决方案，以降低其在生物液中的水平。
