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染色体外的ψ⁺决定簇可抑制酵母中的无义突变。

Extrachromosomal psi+ determinant suppresses nonsense mutations in yeast.

作者信息

Liebman S W, Sherman F

出版信息

J Bacteriol. 1979 Sep;139(3):1068-71. doi: 10.1128/jb.139.3.1068-1071.1979.

DOI:10.1128/jb.139.3.1068-1071.1979
PMID:225301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC218059/
Abstract

The extrachromosomal psi+ determinant in the yeast Saccharomyces cerevisiae enhanced the expression of Mendelian UAA suppressors by 6- to 10-fold. The psi+ determinant by itself is a weak UAA suppressor that caused the production of approximately 1% of the normal level of iso-1-cytochrome c in a strain containing the UAA mutation cycl-72.

摘要

酿酒酵母中的染色体外psi+决定簇使孟德尔UAA抑制子的表达增强了6至10倍。psi+决定簇本身是一个弱UAA抑制子,在含有UAA突变cycl-72的菌株中,它导致产生的异-1-细胞色素c约为正常水平的1%。

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1
Extrachromosomal psi+ determinant suppresses nonsense mutations in yeast.染色体外的ψ⁺决定簇可抑制酵母中的无义突变。
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本文引用的文献

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Genetics and biosynthesis of cytochrome c.细胞色素c的遗传学与生物合成
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Genetic determination of iso-cytochromes c in yeast.酵母中异细胞色素c的遗传决定因素
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Extrachromosomal elements in a super-suppression system of yeast. II. Relations with other extrachromosomal elements.酵母超级抑制系统中的染色体外元件。II. 与其他染色体外元件的关系。
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