BMC Biotechnol. 2012 Apr 25;12:13. doi: 10.1186/1472-6750-12-13.
van der Voet et al. (2011) describe statistical methodology that the European Food Safety Authority expects an applicant to adopt when making a GM crop regulatory submission. Key to their proposed methodology is the inclusion of reference varieties in the experimental design to provide a measure of natural variation amongst commercially grown crops. While taking proper account of natural variation amongst commercial varieties in the safety assessment of GM plants makes good sense, the methodology described by the authors is shown here to be fundamentally flawed and consequently cannot be considered fit for purpose in its current form.
范德沃特等人（2011 年）描述了一种统计方法，欧洲食品安全局（EFSA）期望申请者在提交转基因作物监管申请时采用。他们提出的方法的关键是在实验设计中纳入参照品种，以提供商业种植作物中自然变异的衡量标准。虽然在对转基因植物的安全性评估中适当考虑商业品种中的自然变异是有意义的，但作者所描述的方法在这里被证明存在根本性缺陷，因此不能被认为在其当前形式下适合其目的。
