Department of Anesthesiology, University of Würzburg, Würzburg, Germany.
Med Sci Monit. 2012 May;18(5):BR163-6. doi: 10.12659/msm.882724.
Intra-vesical pressure measurement as the reference standard for assessing intra-abdominal pressures is mainly indirect and discontinuous. We therefore evaluated a motility capsule for continuous intra-abdominal pressure measurement in an animal model with a high probability for capillary leakage and intestinal edema.
MATERIAL/METHODS: Motility capsules were inserted into the stomachs of 8 anesthetized and ventilated pigs. Stomach pH, pressure, and temperature data were wirelessly transmitted to a recorder attached to each animal's abdomen. Intra-gastric pressures measured by the capsule were compared to intra-vesical pressures measured by a pressure transducer system.
The intra-abdominal pressures ranged from 3 to 15 mmHg (7.8 ± 2.4 mmHg [mean ± SD]) measured via the bladder. The capsule pressure recordings ranged from 1 to 3 mmHg (1.7 ± 0.5 mmHg [mean ± SD]). Bland-Altman analysis revealed an unacceptable bias between the 2 methods. The test bias was 6.2 (± 1.4) mmHg and the limits of agreement were from 3.3 to 8.9 mmHg.
Pressures in the stomach as measured by motility capsule underestimated the intra-vesical pressures. Discrepancies between gastric and intra-vesical pressures could be caused by gastric dilatation or different position of the 2 devices to the zero reference point.
作为评估腹腔内压力的参考标准，膀胱内压力测量主要是间接和不连续的。因此，我们在一种毛细血管渗漏和肠水肿可能性较高的动物模型中评估了一种运动胶囊，用于连续测量腹腔内压力。
材料/方法：运动胶囊被插入 8 只麻醉和通气的猪的胃中。胃 pH 值、压力和温度数据通过无线传输到附在每个动物腹部的记录仪上。胶囊测量的胃内压力与压力传感器系统测量的膀胱内压力进行比较。
通过膀胱测量的腹腔内压力范围为 3 至 15 mmHg（7.8 ± 2.4 mmHg[平均值 ± SD]）。胶囊压力记录范围为 1 至 3 mmHg（1.7 ± 0.5 mmHg[平均值 ± SD]）。Bland-Altman 分析显示两种方法之间存在不可接受的偏差。测试偏差为 6.2（± 1.4）mmHg，一致性界限为 3.3 至 8.9 mmHg。
运动胶囊测量的胃内压力低估了膀胱内压力。胃内和膀胱内压力之间的差异可能是由于胃扩张或两个设备相对于零点参考的不同位置引起的。
