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20 月龄婴儿因经媒介传播的恰加斯病导致的进展性巨食管(III 级)。

Advanced megaesophagus (Group III) secondary to vector-borne Chagas disease in a 20-month-old infant.

机构信息

Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, GO.

出版信息

Rev Soc Bras Med Trop. 2012 Mar-Apr;45(2):266-8. doi: 10.1590/s0037-86822012000200026.

DOI:10.1590/s0037-86822012000200026
PMID:22535006
Abstract

The authors report the case of a female infant with Group III (or Grade III) megaesophagus secondary to vector-borne Chagas disease, resulting in severe malnutrition that reversed after surgery (Heller technique). The infant was then treated with the antiparasitic drug benznidazole, and the infection was cured, as demonstrated serologically and parasitologically. After follow-up of several years without evidence of disease, with satisfactory weight and height development, the patient had her first child at age 23, in whom serological tests for Chagas disease yielded negative results. Thirty years after the initial examination, the patient's electrocardiogram, echocardiogram, and chest radiography remained normal.

摘要

作者报告了一例女性婴儿患有 III 组(或 III 级)巨食管症,继发于虫媒传播的恰加斯病,导致严重营养不良,手术后(Heller 技术)得到逆转。婴儿随后接受了驱虫药物苯达唑治疗,感染得到治愈,血清学和寄生虫学检查均证实。经过数年的随访,没有疾病迹象,体重和身高发育良好,患者在 23 岁时生下了第一个孩子,恰加斯病的血清学检查结果为阴性。初次检查 30 年后,患者的心电图、超声心动图和胸部 X 线检查仍正常。

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Blood vessels in ganglia in human esophagus might explain the higher frequency of megaesophagus compared with megacolon.
人类食管神经节中的血管可能解释了与巨结肠相比,巨食管发病率更高的原因。
Rev Inst Med Trop Sao Paulo. 2014 Nov-Dec;56(6):529-32. doi: 10.1590/s0036-46652014000600013.