心脏副神经节瘤的当代外科治疗。
Contemporary surgical management of cardiac paragangliomas.
机构信息
Methodist DeBakey Heart and Vascular Center, Cardiovascular Surgery, Houston, Texas 77030, USA.
出版信息
Ann Thorac Surg. 2012 Jun;93(6):1972-6. doi: 10.1016/j.athoracsur.2012.02.040. Epub 2012 Apr 25.
BACKGROUND
Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells.
METHODS
Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed.
RESULTS
In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%.
CONCLUSIONS
Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.
背景
心脏副神经节瘤是一种非常罕见的嗜铬细胞瘤，来源于神经嵴细胞。
方法
在 2004 年 3 月至 2010 年 10 月期间，我们两家机构共对 7 名接受心脏副神经节瘤切除术的男性患者进行了回顾性分析。
结果
在 5 例患者中，副神经节瘤起源于左心房顶部，在 2 例患者中，起源于主动脉根部。医院死亡率为 14%。
结论
完全手术切除仍然是主要的治疗方法，并且可以治愈，但手术中出血风险很大，通常需要体外循环，并且通常需要复杂的切除技术，包括心脏自体移植。
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