从克隆的C57Bl/6黑色素瘤细胞中分离出三种具有不同生物活性的C型病毒。
Recovery of three distinct biologically active type C viruses from cloned C57Bl/6 melanoma cells.
作者信息
Levy J A, Rutledge F, Dimpfl J, Silagi S
出版信息
J Gen Virol. 1979 May;43(2):283-8. doi: 10.1099/0022-1317-43-2-283.
PMID:225423
Abstract
The genome of a single cell derived from the B16 melanoma contains information for the expression of three distinct biologically active viruses: the N- and B-tropic ecotropic viruses and the xenotropic virus. Their release results in reduction of melanin production. A possible relationship of virus replication to differentiation may be involved.
摘要
源自B16黑色素瘤的单个细胞的基因组包含三种不同生物活性病毒表达的信息：N型和B型嗜亲性病毒以及嗜异性病毒。它们的释放导致黑色素生成减少。可能涉及病毒复制与分化之间的关系。
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