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[股动脉导管刺激强度对全膝关节置换术后镇痛的影响]

[Influence of femoral catheter stimulation intensity on post-surgical analgesia after total knee replacement].

作者信息

Ortiz de la Tabla González R, Martínez Navas A

机构信息

Servicio de Anestesiología y Reanimación del Hospital Universitario de Valme, Sevilla, España.

出版信息

Rev Esp Anestesiol Reanim. 2012 Apr;59(4):187-96. doi: 10.1016/j.redar.2012.02.007. Epub 2012 Apr 28.

Abstract

INTRODUCTION

Stimulating catheters allow the catheter point to be positioned near the nerve, thus reducing the amount of local anaesthetic required for a successful block. There is currently a debate on what is the stimulation intensity required to provide adequate analgesia, although it does seem that if it is obtained with 1mAmp or less the block is more effective. The objective of the study was to demonstrate whether different neurostimulation intensities with the stimulating catheter at femoral nerve level, had an influence on the adequacy of post-surgical analgesia during the 48h after total knee arthroplasty.

MATERIAL AND METHODS

A comparative, prospective and randomised study was conducted on patients subjected to total knee replacement. After surgery with subarachnoid anaesthesia, a continuous femoral block was performed with a stimulating catheter at a neurostimulation intensity 0.2 and 0.5mAmp in Group 1, between 0.6 and 1mAmp in Group 2, equal or higher than 1.1mAmp in Group 3, and in Group 4 the catheter was introduced between 3-5cm without looking for a motor response. A dose of 0.2% ropivacaine 0.4mL/kg and an infusion at 5mL/h, with boluses of 10mL/30min, was administered via the catheter. Sciatic nerve block was also performed on all patients with 20ml of 0.5% ropivacaine. The patient demographics were recorded, as well as, post-surgical analgesia details, sensory and motor block in each area, boluses requested, rescue analgesia, and undesirable effects at 8, 16, 24, 36 and 48h.

RESULTS

A total of 124 patients were included, 32 in Group 1 (25.8%), 21 in Group 2 (16.9%), 31 in Group 3 (25%), and 40 in group 4 (32.3%). The 4 groups were homogeneous as regards age, height, weight and ASA. There were no statistically significant differences found in the post-operative pain, except during movement in the femoral area at 36 hours (p=.032). There were also no statistically significant differences found in the sensory block in the femoral area at 48 hours (p=.019) and in the femoral cutaneous nerve block at 8 hours (p=.049) or at 24 hours (p=.045). As regards motor block, differences were only found in the obturator nerve at 24 hours (p=.016). There were no differences in rescue analgesia, patient controlled analgesia (PCA) boluses requested or administered, except that the number of boluses requested at 16 hours was less in Group 3 (p=.049). There were also no significant differences in undesirable effects or in the level of satisfaction of the patients between the four groups.

CONCLUSIONS

In our study, no influence was found on the level of analgesia provided after knee replacement surgery with the neurostimulation intensity to which the neuromuscular system involved responded when a stimulating catheter is inserted at femoral level.

摘要

引言

刺激导管可使导管尖端位于神经附近,从而减少成功实施阻滞所需的局部麻醉药量。目前对于提供充分镇痛所需的刺激强度存在争议,不过似乎若在1毫安或更低强度下获得该强度,则阻滞效果更佳。本研究的目的是证明在全膝关节置换术后48小时内,在股神经水平使用刺激导管时不同的神经刺激强度是否会对术后镇痛的充分性产生影响。

材料与方法

对接受全膝关节置换的患者进行了一项比较性、前瞻性和随机研究。在蛛网膜下腔麻醉手术后,第1组以0.2和0.5毫安的神经刺激强度使用刺激导管进行连续股神经阻滞,第2组在0.6至1毫安之间,第3组等于或高于1.1毫安,第4组在不寻找运动反应的情况下将导管插入3 - 5厘米。通过导管给予0.2%罗哌卡因0.4毫升/千克的剂量,并以5毫升/小时的速度输注,每30分钟推注10毫升。还对所有患者使用20毫升0.5%罗哌卡因进行坐骨神经阻滞。记录患者的人口统计学数据以及术后镇痛细节、每个区域的感觉和运动阻滞、请求的推注量、补救性镇痛以及在8、16、24、36和48小时时的不良影响。

结果

共纳入124例患者,第1组32例(25.8%),第2组21例(16.9%),第3组31例(25%),第4组40例(32.3%)。四组在年龄、身高、体重和美国麻醉医师协会(ASA)分级方面具有同质性。除了在36小时时股部区域活动期间(p = 0.032),术后疼痛方面未发现统计学上的显著差异。在48小时时股部区域的感觉阻滞(p = 0.019)、8小时(p = 0.049)或24小时(p = 0.045)时股外侧皮神经阻滞方面也未发现统计学上的显著差异。关于运动阻滞,仅在24小时时闭孔神经方面发现差异(p = 0.016)。在补救性镇痛、请求或给予的患者自控镇痛(PCA)推注量方面没有差异,只是第3组在16小时时请求的推注量较少(p = 0.049)。四组在不良影响或患者满意度水平方面也没有显著差异。

结论

在我们的研究中,当在股部水平插入刺激导管时,神经刺激强度对全膝关节置换术后所提供的镇痛水平没有影响,而该强度是所涉及的神经肌肉系统作出反应的强度。

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