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在巴布亚新几内亚推行 HIV 耐药性早期预警指标方面的经验,以改善抗逆转录病毒方案。

Experience in piloting HIV drug resistance early warning indicators to improve the antiretroviral program in Papua New Guinea.

机构信息

HIV/AIDS Program, National Department of Health, Waigani, National Capital District, Papua New Guinea.

出版信息

Clin Infect Dis. 2012 May;54 Suppl 4:S303-5. doi: 10.1093/cid/cir994.

DOI:10.1093/cid/cir994
PMID:22544192
Abstract

In 2009, World Health Organization human immunodeficiency virus drug resistance early warning indicator monitoring was piloted at 2 large antiretroviral therapy (ART) clinics in Papua New Guinea: Heduru Clinic in Port Moresby and Tininga Clinic in Mount Hagen. Results demonstrated that both Heduru and Tininga clinics met internationally suggested targets for prescribing appropriate first-line ART regimens in accordance with national ART guidelines, retention on first-line ART at 12 months, and drug supply continuity. However, both clinics failed to achieve suggested targets for rates of loss to follow-up and on-time pill pickup. Reasons for poor clinic performance on loss to follow-up and on-time pill pickup were explored, and appropriate corrective actions were implemented.

摘要

2009 年,世界卫生组织在巴布亚新几内亚的 2 个大型抗逆转录病毒治疗 (ART) 诊所进行了人类免疫缺陷病毒耐药性早期预警指标监测试点:莫尔斯比港的赫德鲁诊所和芒特哈根的廷宁加诊所。结果表明,赫德鲁和廷宁加诊所均符合国际上建议的根据国家 ART 指南规定适当一线 ART 方案、12 个月时保留一线 ART 和药物供应连续性的目标。然而,这两个诊所都未能实现建议的失访率和按时取药率目标。对诊所失访和按时取药不良表现的原因进行了探讨,并实施了适当的纠正措施。

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