• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

光动力疗法在潜在恶性和恶性口腔疾病管理中的应用

Photodynamic therapy in the management of potentially malignant and malignant oral disorders.

作者信息

Jerjes Waseem, Hamdoon Zaid, Hopper Colin

机构信息

Department of Surgery, Dijla University College, Baghdad, Iraq.

出版信息

Head Neck Oncol. 2012 Apr 30;4:16. doi: 10.1186/1758-3284-4-16.

DOI:10.1186/1758-3284-4-16
PMID:22546491
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3629701/
Abstract

Photodynamic therapy (PDT) is a minimally-invasive surgical tool successfully targeting premalignant and malignant disorders in the head and neck, gastrointestinal tract, lungs and skin with greatly reduced morbidity and disfigurement. The technique is simple, can commonly be carried out in outpatient clinics, and is highly acceptable to patients. The role of photodynamic therapy in the management of oral potentially malignant disorders and early oral cancer is being discussed.

摘要

光动力疗法（PDT）是一种微创外科工具，已成功用于治疗头颈部、胃肠道、肺部及皮肤的癌前病变和恶性疾病，且发病率和毁容风险大幅降低。该技术操作简单，通常可在门诊进行，患者接受度高。目前正在探讨光动力疗法在口腔潜在恶性疾病和早期口腔癌治疗中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c7a/3629701/e3c8a1aa760f/1758-3284-4-16-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c7a/3629701/e3c8a1aa760f/1758-3284-4-16-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c7a/3629701/e3c8a1aa760f/1758-3284-4-16-1.jpg

相似文献

1
Photodynamic therapy in the management of potentially malignant and malignant oral disorders.光动力疗法在潜在恶性和恶性口腔疾病管理中的应用
Head Neck Oncol. 2012 Apr 30;4:16. doi: 10.1186/1758-3284-4-16.
2
Systemic and topical photodynamic therapy (PDT) on oral mucosa lesions: an overview.系统和局部光动力疗法（PDT）治疗口腔黏膜病变：概述。
J Biol Regul Homeost Agents. 2018 Jan-Feb;32(2 Suppl. 1):123-126.
3
The application of photodynamic therapy in the head and neck.光动力疗法在头颈部的应用。
Dent Update. 2007 Oct;34(8):478-80, 483-4, 486. doi: 10.12968/denu.2007.34.8.478.
4
Photodynamic Therapy in Oral Cancer: A Narrative Review.光动力疗法在口腔癌中的应用：一项叙述性综述。
Photobiomodul Photomed Laser Surg. 2023 Jun;41(6):248-264. doi: 10.1089/photob.2023.0030. Epub 2023 May 24.
5
Photodynamic therapy for oral potentially malignant disorders.光动力疗法治疗口腔潜在恶性疾病。
Photodiagnosis Photodyn Ther. 2019 Dec;28:146-152. doi: 10.1016/j.pdpdt.2019.08.005. Epub 2019 Aug 5.
6
Photodynamic therapy in oral potentially malignant disorders-Critical literature review of existing protocols.口腔潜在恶性疾病的光动力疗法——现有方案的关键文献综述。
Photodiagnosis Photodyn Ther. 2017 Dec;20:125-129. doi: 10.1016/j.pdpdt.2017.09.007. Epub 2017 Sep 14.
7
Revisiting the evidence of photodynamic therapy for oral potentially malignant disorders and oral squamous cell carcinoma: An overview of systematic reviews.重新审视光动力疗法治疗口腔潜在恶性疾病和口腔鳞状细胞癌的证据：系统评价概述。
Photodiagnosis Photodyn Ther. 2023 Jun;42:103531. doi: 10.1016/j.pdpdt.2023.103531. Epub 2023 Mar 22.
8
Photodynamic therapy in the management of basal cell carcinoma: Retrospective evaluation of outcome.光动力疗法在基底细胞癌治疗中的应用：回顾性疗效评估。
Photodiagnosis Photodyn Ther. 2017 Sep;19:22-27. doi: 10.1016/j.pdpdt.2017.04.008. Epub 2017 Apr 22.
9
[Photodynamic therapy of the oral mucosa].[口腔黏膜的光动力疗法]
Ned Tijdschr Tandheelkd. 1997 Oct;104(10):377-80.
10
Cyclooxygenase-2 is a possible target of treatment approach in conjunction with photodynamic therapy for various disorders in skin and oral cavity.环氧化酶-2可能是一种与光动力疗法联合用于治疗皮肤和口腔各种疾病的治疗靶点。
Br J Dermatol. 2004 Aug;151(2):472-80. doi: 10.1111/j.1365-2133.2004.06053.x.

引用本文的文献

1
Toluidine Blue and Chlorin-e6 Mediated Photodynamic Therapy in the Treatment of Oral Potentially Malignant Disorders: A Systematic Review.甲苯胺蓝与二氢卟吩-e6介导的光动力疗法治疗口腔潜在恶性疾病的系统评价
Int J Mol Sci. 2025 Mar 12;26(6):2528. doi: 10.3390/ijms26062528.
2
Advanced Lasers and Their Applications in Dentistry.先进激光及其在牙科中的应用。
Dent J (Basel). 2025 Jan 16;13(1):37. doi: 10.3390/dj13010037.
3
Localized intratumoral delivery of immunomodulators for oral cancer and oral potentially malignant disorders.

本文引用的文献

1
Photodynamic therapy outcome for T1/T2 N0 oral squamous cell carcinoma.T1/T2 N0期口腔鳞状细胞癌的光动力治疗效果
Lasers Surg Med. 2011 Aug;43(6):463-9. doi: 10.1002/lsm.21071.
2
Interstitial PDT for vascular anomalies.用于血管异常的间质光动力疗法
Lasers Surg Med. 2011 Jul;43(5):357-65. doi: 10.1002/lsm.21058.
3
Photodynamic therapy outcome for oral dysplasia.口腔发育异常的光动力治疗效果
局部瘤内递送免疫调节剂治疗口腔癌和口腔潜在恶性疾病。
Oral Oncol. 2024 Nov;158:106986. doi: 10.1016/j.oraloncology.2024.106986. Epub 2024 Aug 12.
4
Photodynamic therapy, priming and optical imaging: Potential co-conspirators in treatment design and optimization - a Thomas Dougherty Award for Excellence in PDT paper.光动力疗法、预处理与光学成像：治疗设计与优化中的潜在协同因素——一篇荣获托马斯·多尔蒂光动力疗法卓越奖的论文
J Porphyr Phthalocyanines. 2020 Nov-Dec;24(11n12):1320-1360. doi: 10.1142/s1088424620300098.
5
From Basic Mechanisms to Clinical Research: Photodynamic Therapy Applications in Head and Neck Malignancies and Vascular Anomalies.从基础机制到临床研究：光动力疗法在头颈部恶性肿瘤和血管异常中的应用
J Clin Med. 2021 Sep 26;10(19):4404. doi: 10.3390/jcm10194404.
6
Lesion oxygenation associates with clinical outcomes in premalignant and early stage head and neck tumors treated on a phase 1 trial of photodynamic therapy.在光动力疗法 1 期临床试验中治疗的癌前和早期头颈部肿瘤中，病变氧合与临床结局相关。
Photodiagnosis Photodyn Ther. 2018 Mar;21:28-35. doi: 10.1016/j.pdpdt.2017.10.015. Epub 2017 Nov 4.
7
Photodynamic Therapy - A Non-invasive Treatment Modality for Precancerous Lesions.光动力疗法——一种针对癌前病变的非侵入性治疗方式。
J Lasers Med Sci. 2016 Winter;7(1):30-6. doi: 10.15171/jlms.2016.07. Epub 2016 Jan 7.
8
Combination of Sonodynamic and Photodynamic Therapy against Cancer Would Be Effective through Using a Regulated Size of Nanoparticles.通过使用尺寸可控的纳米颗粒，声动力与光动力联合治疗癌症将行之有效。
Nanosci Nanoeng. 2016 Feb;4(1):1-11. doi: 10.13189/nn.2016.040101.
9
Monitoring photodynamic therapy of head and neck malignancies with optical spectroscopies.利用光谱学监测头颈部恶性肿瘤的光动力疗法
World J Clin Cases. 2013 Jun 16;1(3):96-105. doi: 10.12998/wjcc.v1.i3.96.
10
Solitary giant neurofibroma of the neck subjected to photodynamic therapy: case study.颈部孤立性巨大神经纤维瘤接受光动力治疗：病例报告
Head Neck Oncol. 2012;4:30. doi: 10.1186/1758-3284-4-30. Epub 2012 Jun 6.
Lasers Surg Med. 2011 Mar;43(3):192-9. doi: 10.1002/lsm.21036.
4
Photodynamic therapy for large superficial squamous cell carcinoma of the esophagus.光动力疗法治疗食管大面积浅表性鳞状细胞癌。
Gastrointest Endosc. 2011 Jan;73(1):1-6. doi: 10.1016/j.gie.2010.08.049. Epub 2010 Nov 12.
5
A systematic review of photodynamic therapy in the treatment of pre-cancerous skin conditions, Barrett's oesophagus and cancers of the biliary tract, brain, head and neck, lung, oesophagus and skin.光动力疗法治疗癌前皮肤状况、巴雷特食管和胆道、脑、头颈部、肺、食管和皮肤癌症的系统评价。
Health Technol Assess. 2010 Jul;14(37):1-288. doi: 10.3310/hta14370.
6
Photodynamic laser therapy for lesions in the airway.光动力激光疗法治疗气道病变。
Ann Thorac Surg. 2010 Jun;89(6):1744-8; discussion 1748-9. doi: 10.1016/j.athoracsur.2010.02.025.
7
Clinicopathological parameters, recurrence, locoregional and distant metastasis in 115 T1-T2 oral squamous cell carcinoma patients.115例T1-T2期口腔鳞状细胞癌患者的临床病理参数、复发情况、局部区域及远处转移情况
Head Neck Oncol. 2010 Apr 20;2:9. doi: 10.1186/1758-3284-2-9.
8
Potentially malignant disorders of the oral and oropharyngeal mucosa; present concepts of management.口腔和口咽黏膜的潜在恶性疾病；当前的治疗理念。
Oral Oncol. 2010 Jun;46(6):423-5. doi: 10.1016/j.oraloncology.2010.02.016. Epub 2010 Mar 21.
9
Ultrasound-guided photodynamic therapy for deep seated pathologies: prospective study.
Lasers Surg Med. 2009 Nov;41(9):612-21. doi: 10.1002/lsm.20853.
10
Photodynamic therapy for head and neck dysplasia and cancer.用于头颈部发育异常和癌症的光动力疗法。
Arch Otolaryngol Head Neck Surg. 2009 Aug;135(8):784-8. doi: 10.1001/archoto.2009.98.