Millet P, Collins W E, Monken C E, Brown B G
Malaria Branch, Centers for Disease Control, U.S. Department of Health and Human Services, Atlanta, Georgia 30333.
J Parasitol. 1990 Dec;76(6):923-5.
Exoerythrocytic stages of Plasmodium knowlesi were obtained in primary culture of rhesus monkey hepatocytes. The development of a single parasite was followed with phase contrast microscopy until release of merozoites in slightly less than 5 days. This direct observation may offer opportunities to determine visually factors that may influence specific steps of schizont development.
诺氏疟原虫的红细胞外期在恒河猴肝细胞原代培养物中获得。用相差显微镜观察单个疟原虫的发育过程,直至裂殖子在略少于5天的时间内释放。这种直接观察可能为直观地确定影响裂殖体发育特定步骤的因素提供机会。