Wrobel Beate Maria, Schubert Gernot, Hörmann Markus, Strohmaier Walter Ludwig
Department of Urology and Paediatric Urology, Klinikum Coburg, Ketschendorfer Strasse 33, 96450 Coburg, Germany.
Adv Urol. 2012;2012:438707. doi: 10.1155/2012/438707. Epub 2012 Apr 5.
Introduction. Several studies showed an association of overweight and obesity with calcium oxalate stone disease (CaOx). However, there are no sufficient data on the influence of body weight on the course of the disease and the recurrence rate. Patients and Methods. N = 100 consecutive stone formers with pure CaOx were studied. Different parameters were investigated. According to the BMI, patients were divided into three groups: (1) BMI ≤ 25; (2) BMI 25.1-30; (3) BMI > 30. Results. N = 32 patients showed a BMI ≤ 25, n = 42 patients showed a BMI of 25.1-30 and n = 26 patients showed a BMI ≥ 30. The groups differed significantly concerning BMI (by definition), urine pH, and urine citrate. The recurrence rate was not significantly different. Discussion. Our study demonstrated that body weight negatively influences single risk factors in CaOx, but obesity is not a predictor for the risk of recurrence in CaOx.
引言。多项研究表明超重和肥胖与草酸钙结石病（CaOx）有关。然而，关于体重对该病病程和复发率影响的数据并不充分。
患者与方法。对连续100例单纯草酸钙结石患者进行了研究。调查了不同参数。根据体重指数（BMI），患者被分为三组：（1）BMI≤25；（2）BMI 25.1 - 30；（3）BMI>30。
结果。32例患者BMI≤25，42例患者BMI为25.1 - 30，26例患者BMI≥30。各组在BMI（根据定义）、尿pH值和尿枸橼酸盐方面存在显著差异。复发率无显著差异。
讨论。我们的研究表明体重对草酸钙结石的单一危险因素有负面影响，但肥胖并非草酸钙结石复发风险的预测因素。
