Rotavirus Vaccine Program, PATH, Seattle, WA, USA.
Expert Rev Vaccines. 2012 Apr;11(4):407-9. doi: 10.1586/erv.12.9.
The 6th Vaccines for Enteric Diseases Symposium was held in Cannes, France, on 14-16 September 2011, drawing approximately 200 vaccine developers, academics and public health experts globally. Infectious diarrhea is a worldwide problem with high mortality and morbidity, particularly among children in the developing world. The WHO estimated approximately 8.8 million deaths in 2008 in young children aged 1-59 months, of which almost 2 million could be attributed to diarrheal illnesses--more than malaria, HIV/AIDS and TB combined. New breakthroughs in vaccine development, early clinical trials for the enterotoxigenic Escherichia coli, Shigella, noroviruses and conjugate typhoid vaccines, and updates on the implementation of rotavirus, cholera and typhoid vaccines were reported.
第六届肠道疾病疫苗研讨会于 2011 年 9 月 14 日至 16 日在法国戛纳举行,来自全球约 200 名疫苗研发人员、学者和公共卫生专家参加了会议。感染性腹泻是一个全球性问题,具有高死亡率和发病率,特别是在发展中国家的儿童中。据世界卫生组织估计,2008 年 1-59 月龄的幼儿中有约 880 万人死亡,其中近 200 万人可归因于腹泻病——超过疟疾、艾滋病毒/艾滋病和结核病的总和。会上报告了疫苗开发的新突破、肠产毒性大肠杆菌、志贺氏菌、诺如病毒和结合型伤寒疫苗的早期临床试验,以及轮状病毒、霍乱和伤寒疫苗实施情况的最新进展。