[Mechanisms of the effects of physical training on the functional state of blood platelets in patients with ischemic heart disease].

The platelet-vascular hemostasis and lipid peroxidation were examined in 60 male patients with coronary heart disease during their 30-day daily bicycle ergometric exercise performance. During the exercise, the patients were demonstrated to have a lower platelet aggregability. The factors that contribute to a physical training-induced decrease in the functional activity of platelets include lower levels of cholesterol, thrombin, lower blood oxidative activity and higher concentrations of prostaglandin I2 and high density lipoproteins.